AIM: To describe the characteristics, practice patterns, targets and outcome of the Type 2 diabetic patients (DM 2) in peritoneal dialysis (PD) and to compare them with non-diabetic ones. METHODS: Prospective cohort study of every incident PD patient in a regional public health care system (2003-2006). We prospectively collected baseline data, hospital admissions, peritonitis, transplants, CV events and deaths. Every six months PD prescription data and results on efficacy, anaemia, blood pressure (BP) were collected. RESULTS: DM 2 patients (n = 65) were older and presented a higher rate of previous CV events (60.9% vs. 17.7% p<0001) than non-DM patients (n = 376) and worse BP control at inclusion on PD. There were no differences in dialysis efficacy targets and anaemia management. HOSPITAL ADMISSIONS: DM 2 patients present higher hospitalisation rates 1.1 [0.9-1.4] than NoDM ones 0.6 [0.5-0.7] admissions per year at risk. Survival: DM 2 patients present lower PD-technique survival than No DM ones (870 vs. 1002 days Kaplan-Mayer estimation p = 0.009) and higher annual mortality rate (13.7 vs. 4.1%, p: 0.021) with a crude mortality hazard ratio (HR) of 2.5 [1.1-5.6] after correction by age. However, the best predictive model for mortality by Cox proportional hazards model includes age, existence of previous CV events and forced inclusion on PD and excludes DM 2. The association between DM 2 and CV events ruled out DM 2 from the multivariate risk model. CONCLUSION: Type 2 DM patients had a higher prevalence of previous CV events, and a worse global outcome. Previous CV events may explain part of this risk.
AIM: To describe the characteristics, practice patterns, targets and outcome of the Type 2 diabeticpatients (DM 2) in peritoneal dialysis (PD) and to compare them with non-diabetic ones. METHODS: Prospective cohort study of every incident PDpatient in a regional public health care system (2003-2006). We prospectively collected baseline data, hospital admissions, peritonitis, transplants, CV events and deaths. Every six months PD prescription data and results on efficacy, anaemia, blood pressure (BP) were collected. RESULTS:DM 2 patients (n = 65) were older and presented a higher rate of previous CV events (60.9% vs. 17.7% p<0001) than non-DMpatients (n = 376) and worse BP control at inclusion on PD. There were no differences in dialysis efficacy targets and anaemia management. HOSPITAL ADMISSIONS: DM 2 patients present higher hospitalisation rates 1.1 [0.9-1.4] than NoDM ones 0.6 [0.5-0.7] admissions per year at risk. Survival: DM 2 patients present lower PD-technique survival than No DM ones (870 vs. 1002 days Kaplan-Mayer estimation p = 0.009) and higher annual mortality rate (13.7 vs. 4.1%, p: 0.021) with a crude mortality hazard ratio (HR) of 2.5 [1.1-5.6] after correction by age. However, the best predictive model for mortality by Cox proportional hazards model includes age, existence of previous CV events and forced inclusion on PD and excludes DM 2. The association between DM 2 and CV events ruled out DM 2 from the multivariate risk model. CONCLUSION: Type 2 DMpatients had a higher prevalence of previous CV events, and a worse global outcome. Previous CV events may explain part of this risk.
Authors: P Cotovio; A Rocha; M J Carvalho; L Teixeira; D Mendonça; A Cabrita; A Rodrigues Journal: Perit Dial Int Date: 2014-01-02 Impact factor: 1.756
Authors: Ana María Gómez; Santiago Vallejo; Freddy Ardila; Oscar M Muñoz; Álvaro J Ruiz; Mauricio Sanabria; Alfonso Bunch; Elly Morros; Laura Kattah; Maira García-Jaramillo; Fabián León-Vargas Journal: J Diabetes Sci Technol Date: 2017-09-20
Authors: Darío Janeiro; Jose Portolés; Ana María Tato; Paula López-Sánchez; Gloria Del Peso; Maite Rivera; Inés Castellano; Maria J Fernández-Reyes; Vanessa Pérez-Gómez; Mayra Ortega; Patricia Martínez-Miguel; Carmen Felipe; Guadalupe Caparrós; Alberto Ortiz; Rafael Selgas Journal: Perit Dial Int Date: 2014-10-07 Impact factor: 1.756