Literature DB >> 19666057

Post-translational modifications in Plasmodium: more than you think!

Duk-Won Doug Chung1, Nadia Ponts, Serena Cervantes, Karine G Le Roch.   

Abstract

Recent evidences indicate that transcription in Plasmodium may be hard-wired and rigid, deviating from the classical model of transcriptional gene regulation. Thus, it is important that other regulatory pathways be investigated as a comprehensive effort to curb the deadly malarial parasite. Research in post-translational modifications in Plasmodium is an emerging field that may provide new venues for drug discovery and potential new insights into how parasitic protozoans regulate their life cycle. Here, we discuss the recent findings of post-translational modifications in Plasmodium.

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Year:  2009        PMID: 19666057     DOI: 10.1016/j.molbiopara.2009.08.001

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN: 0166-6851            Impact factor:   1.759


  23 in total

1.  Unraveling the ubiquitome of the human malaria parasite.

Authors:  Nadia Ponts; Anita Saraf; Duk-Won D Chung; Alona Harris; Jacques Prudhomme; Michael P Washburn; Laurence Florens; Karine G Le Roch
Journal:  J Biol Chem       Date:  2011-09-19       Impact factor: 5.157

2.  Identification of three ookinete-specific genes and evaluation of their transmission-blocking potentials in Plasmodium berghei.

Authors:  Wenqi Zheng; Xu Kou; Yunting Du; Fei Liu; Chunyun Yu; Takafumi Tsuboi; Qi Fan; Enjie Luo; Yaming Cao; Liwang Cui
Journal:  Vaccine       Date:  2016-04-12       Impact factor: 3.641

3.  Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems.

Authors:  Katherine H Reiter; Anita Ramachandran; Xue Xia; Lauren E Boucher; Jürgen Bosch; Michael J Matunis
Journal:  J Biol Chem       Date:  2015-12-23       Impact factor: 5.157

4.  Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 in Leishmania donovani results in loss of β-oxidation of fatty acids and blocks cell division in the amastigote stage.

Authors:  Sreenivas Gannavaram; Patricia S Connelly; Mathew P Daniels; Robert Duncan; Poonam Salotra; Hira L Nakhasi
Journal:  Mol Microbiol       Date:  2012-08-16       Impact factor: 3.501

5.  Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum.

Authors:  Bernardo Javier Foth; Neng Zhang; Balbir Kaur Chaal; Siu Kwan Sze; Peter Rainer Preiser; Zbynek Bozdech
Journal:  Mol Cell Proteomics       Date:  2011-05-10       Impact factor: 5.911

6.  PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium.

Authors:  Min Zhang; Satish Mishra; Ramanavelan Sakthivel; Margarito Rojas; Ravikant Ranjan; William J Sullivan; Beatriz M A Fontoura; Robert Ménard; Thomas E Dever; Victor Nussenzweig
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-21       Impact factor: 11.205

7.  Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

Authors:  Germán Plata; Tzu-Lin Hsiao; Kellen L Olszewski; Manuel Llinás; Dennis Vitkup
Journal:  Mol Syst Biol       Date:  2010-09-07       Impact factor: 11.429

8.  Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections.

Authors:  Cathrine Holm Olesen; Karima Brahimi; Brian Vandahl; Susana Lousada-Dietrich; Prajakta S Jogdand; Lasse S Vestergaard; Daniel Dodoo; Peter Højrup; Michael Christiansen; Severin Olesen Larsen; Subhash Singh; Michael Theisen
Journal:  Malar J       Date:  2010-10-26       Impact factor: 2.979

9.  Atypical mitogen-activated protein kinase phosphatase implicated in regulating transition from pre-S-Phase asexual intraerythrocytic development of Plasmodium falciparum.

Authors:  Bharath Balu; Christopher Campbell; Jennifer Sedillo; Steven Maher; Naresh Singh; Phaedra Thomas; Min Zhang; Alena Pance; Thomas D Otto; Julian C Rayner; John H Adams
Journal:  Eukaryot Cell       Date:  2013-06-28

10.  Identification of biochemically distinct properties of the small ubiquitin-related modifier (SUMO) conjugation pathway in Plasmodium falciparum.

Authors:  Katherine Reiter; Debaditya Mukhopadhyay; Hong Zhang; Lauren E Boucher; Nirbhay Kumar; Jürgen Bosch; Michael J Matunis
Journal:  J Biol Chem       Date:  2013-08-13       Impact factor: 5.157

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