BACKGROUND: There is no standardised definition of a pulmonary exacerbation in cystic fibrosis (CF). In attempting to achieve standardised criteria it is important to identify patient-reported indicators. METHODS: Interviews were undertaken with 47 adults with CF. Participants were asked to report symptoms experienced during a pulmonary exacerbation in two ways: the first symptoms they become aware of, and how they subsequently recognised when they were improving. RESULTS: A range of systemic and respiratory symptoms were reported. Their relative importance varied by severity of disease. The severity and subsequent improvement of an exacerbation was often described as limitations on their activities. CONCLUSION: These preliminary data suggest that patient-reported indicators of a pulmonary exacerbation may not be the same for all adults with CF. Whether different indicators are associated with specific demographic or clinical variables remains to be evaluated.
BACKGROUND: There is no standardised definition of a pulmonary exacerbation in cystic fibrosis (CF). In attempting to achieve standardised criteria it is important to identify patient-reported indicators. METHODS: Interviews were undertaken with 47 adults with CF. Participants were asked to report symptoms experienced during a pulmonary exacerbation in two ways: the first symptoms they become aware of, and how they subsequently recognised when they were improving. RESULTS: A range of systemic and respiratory symptoms were reported. Their relative importance varied by severity of disease. The severity and subsequent improvement of an exacerbation was often described as limitations on their activities. CONCLUSION: These preliminary data suggest that patient-reported indicators of a pulmonary exacerbation may not be the same for all adults with CF. Whether different indicators are associated with specific demographic or clinical variables remains to be evaluated.
Authors: Alex H Gifford; Lisa A Moulton; Dana B Dorman; Gordana Olbina; Mark Westerman; H Worth Parker; Bruce A Stanton; George A O'Toole Journal: Clin Transl Sci Date: 2012-06-01 Impact factor: 4.689
Authors: Mirai Mizutani; Julie Bérubé; Heather G Ahlgren; Joanie Bernier; Elias Matouk; Dao Nguyen; Simon Rousseau Journal: ERJ Open Res Date: 2017-06-19
Authors: Elias Matouk; Dao Nguyen; Andrea Benedetti; Joanie Bernier; James Gruber; Jennifer Landry; Simon Rousseau; Heather G Ahlgren; Larry C Lands; Gabriella Wojewodka; Danuta Radzioch Journal: J Pulm Respir Med Date: 2016-10-14
Authors: Kathleen McElhone; Janice Abbott; Chris Sutton; Montana Mullen; Peter Lanyon; Anisur Rahman; Chee-Seng Yee; Mohammed Akil; Ian N Bruce; Yasmeen Ahmad; Caroline Gordon; Lee-Suan Teh Journal: Arthritis Care Res (Hoboken) Date: 2016-09-02 Impact factor: 4.794