Literature DB >> 19663826

International variations in infection supportive care practices for paediatric patients with acute myeloid leukaemia.

Thomas Lehrnbecher1, Marie-Chantal Ethier, Theoklis Zaoutis, Ursula Creutzig, Alan Gamis, Dirk Reinhardt, Richard Aplenc, Lillian Sung.   

Abstract

This study described infection-related supportive care practices amongst centres participating in two large paediatric acute myeloid leukaemia (AML) cooperative groups, Children's Oncology Group (COG) and Berlin-Frankfurt-Muenster (BFM). We surveyed 216 COG and 55 BFM institutions. The overall survey response rate was 83.8%. Antibacterial prophylaxis was more common among BFM (15/46, 32.6%) compared to COG (24/180, 13.3%, P < 0.0001) institutions. Antifungal prophylaxis also was more common among BFM (42/46, 91.3%) compared to COG (137/178, 77.0%, P = 0.03). There were systematic differences in infection-related supportive care practices. This information may be used to encourage harmonization of supportive care practices and future randomized trials.

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Year:  2009        PMID: 19663826     DOI: 10.1111/j.1365-2141.2009.07844.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  31 in total

1.  Treatment-related adverse events associated with a modified UK ALLR3 induction chemotherapy backbone for childhood relapsed/refractory acute lymphoblastic leukemia.

Authors:  Weili Sun; Etan Orgel; Jemily Malvar; Richard Sposto; Jennifer J Wilkes; Rebecca Gardner; Vanessa P Tolbert; Alison Smith; Minjun Hur; Jill Hoffman; Susan R Rheingold; Michael J Burke; Alan S Wayne
Journal:  Pediatr Blood Cancer       Date:  2016-07-20       Impact factor: 3.167

2.  Cost-effectiveness of levofloxacin prophylaxis against bacterial infection in pediatric patients with acute myeloid leukemia.

Authors:  Meghan McCormick; Erika Friehling; Ramasubramanian Kalpatthi; Nalyn Siripong; Kenneth Smith
Journal:  Pediatr Blood Cancer       Date:  2020-07-25       Impact factor: 3.167

3.  Critical review of current clinical practice guidelines for antifungal therapy in paediatric haematology and oncology.

Authors:  Jessica E Morgan; Hadeel Hassan; Julia V Cockle; Christopher Lethaby; Beki James; Robert S Phillips
Journal:  Support Care Cancer       Date:  2016-09-11       Impact factor: 3.603

Review 4.  Antifungal stewardship considerations for adults and pediatrics.

Authors:  Rana F Hamdy; Theoklis E Zaoutis; Susan K Seo
Journal:  Virulence       Date:  2016-09-02       Impact factor: 5.882

5.  Effect of age and body weight on toxicity and survival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004.

Authors:  Ditte J A Løhmann; Jonas Abrahamsson; Shau-Yin Ha; Ólafur G Jónsson; Minna Koskenvuo; Birgitte Lausen; Josefine Palle; Bernward Zeller; Henrik Hasle
Journal:  Haematologica       Date:  2016-07-28       Impact factor: 9.941

6.  Prevention of bacterial infection in pediatric oncology: what do we know, what can we learn?

Authors:  Sarah Alexander; Michael Nieder; Danielle M Zerr; Brian T Fisher; Christopher C Dvorak; Lillian Sung
Journal:  Pediatr Blood Cancer       Date:  2011-11-18       Impact factor: 3.167

Review 7.  Antifungal prophylaxis in pediatric hematology/oncology: new choices & new data.

Authors:  Christopher C Dvorak; Brian T Fisher; Lillian Sung; William J Steinbach; Michael Nieder; Sarah Alexander; Theoklis E Zaoutis
Journal:  Pediatr Blood Cancer       Date:  2011-11-18       Impact factor: 3.167

8.  Predictors of antiemetic alteration in pediatric acute myeloid leukemia.

Authors:  Jason L Freedman; Jennifer Faerber; Tammy I Kang; Dingwei Dai; Brian T Fisher; Yuan-Shung Huang; Yimei Li; Richard Aplenc; Chris Feudtner
Journal:  Pediatr Blood Cancer       Date:  2014-06-17       Impact factor: 3.167

9.  Effectiveness of supportive care measures to reduce infections in pediatric AML: a report from the Children's Oncology Group.

Authors:  Lillian Sung; Richard Aplenc; Todd A Alonzo; Robert B Gerbing; Thomas Lehrnbecher; Alan S Gamis
Journal:  Blood       Date:  2013-03-07       Impact factor: 22.113

Review 10.  Fungal infections in children with haematologic malignancies and stem cell transplant recipients.

Authors:  William R Otto; Abby M Green
Journal:  Br J Haematol       Date:  2020-03-11       Impact factor: 6.998

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