Literature DB >> 19662580

In vitro inhibitory effects of palmatine from Enantia chlorantha on Trypanosoma cruzi and Leishmania infantum.

Ernestine Tchouboun Nkwengoua1, Igor Ngantchou, Barthélemy Nyasse, Colette Denier, Casimir Blonski, Bernd Schneider.   

Abstract

In an attempt to establish the components responsible for the use of Enantia chlorantha against cutaneous leishmaniasis in local traditional medicine, a well-known palmatine has been isolated in substantial amounts from a methanolic bark extract of this plant species. Palmatine therein obtained exhibited a significant inhibitory activity on growth of both Trypanosoma cruzi (IC(50) 0.068 microM) and Leishmania infantum (IC(50) 0.79 microM).

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Year:  2009        PMID： 19662580     DOI： 10.1080/14786410902726241

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  5 in total

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Journal:  Chem Rev       Date:  2014-11-03       Impact factor: 60.622

2.  9-O-Ethyl-berberrubinium iodide monohydrate.

Authors:  Peter Grundt; Jennifer Pernat; Bogdana Krivogorsky; Melanie A Halverson; Steven M Berry
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-18

3.  Activity of natural and synthetic polygodial derivatives against Trypanosoma cruzi amastigotes, trypomastigotes and epimastigotes.

Authors:  Danielle N Turner; Jeremy Just; Ramesh Dasari; Jason A Smith; Alex C Bissember; Alexander Kornienko; Snezna Rogelj
Journal:  Nat Prod Res       Date:  2019-04-28       Impact factor: 2.861

Review 4.  A Review on Traditionally Used African Medicinal Plant Annickia chlorantha, Its Phytochemistry, and Anticancer Potential.

Authors:  Paromita Sarbadhikary; Blassan P George
Journal:  Plants (Basel)       Date:  2022-09-02

5.  Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor.

Authors:  Jonathan S Marchant; Wayne W Harding; John D Chan
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2018-09-28       Impact factor: 4.077
  5 in total

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