Literature DB >> 19662255

Sc(OTf)(3)-catalyzed condensation of 2-alkyl-N-tosylaziridine with aldehydes or ketones: an efficient synthesis of 5-alkyl-1,3-oxazolidines.

Byungman Kang1, Aaron W Miller, Sandra Goyal, SonBinh T Nguyen.   

Abstract

Sc(OTf)(3) effectively catalyzes the condensation of 2-alkyl-N-tosylaziridine with a wide variety of aldehydes and ketones, producing 5-alkyl-1,3-oxazolidines in good yields and excellent regioselectivity at catalyst loadings as low as 1 mol%.

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Year:  2009        PMID： 19662255     DOI： 10.1039/b902647a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Stereoselective synthesis of substituted 1,3-oxazolidines via Pd-catalyzed carboamination reactions of O-vinyl-1,2-amino alcohols.

Authors:  Amanda F Ward; John P Wolfe
Journal:  Org Lett       Date:  2011-08-03       Impact factor: 6.005

2.  Combining photochemistry and catalysis: rapid access to sp3 - rich polyheterocycles from simple pyrroles.

Authors:  Emma E Blackham; Jonathan P Knowles; Jonathan Burgess; Kevin I Booker-Milburn
Journal:  Chem Sci       Date:  2016-01-04       Impact factor: 9.825

3.  Phosphine-Promoted [4 + 3] Annulation of Allenoate with Aziridines for Synthesis of Tetrahydroazepines: Phosphine-Dependent [3 + 3] and [4 + 3] Pathways.

Authors:  Honglei Liu; Yan Lin; Yan Zhao; Miaoren Xiao; Leijie Zhou; Qijun Wang; Cheng Zhang; Dongqi Wang; Ohyun Kwon; Hongchao Guo
Journal:  RSC Adv       Date:  2019-01-09       Impact factor: 4.036
  3 in total

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