Literature DB >> 19659248

Internal friction and nonequilibrium unfolding of polymeric globules.

Alfredo Alexander-Katz1, Hirofumi Wada, Roland R Netz.   

Abstract

The stretching response of a single collapsed homopolymer is studied using Brownian dynamic simulations. The irreversibly dissipated work is found to be dominated by internal friction effects below the collapse temperature, and the internal viscosity grows exponentially with the effective cohesive strength between monomers. These results explain friction effects of globular DNA and are relevant for dissipation at intermediate stages of protein folding.

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Year:  2009        PMID： 19659248     DOI： 10.1103/PhysRevLett.103.028102

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN： 0031-9007            Impact factor:   9.161


  7 in total

1.  Conformational dynamics and internal friction in homopolymer globules: equilibrium vs. non-equilibrium simulations.

Authors:  T R Einert; C E Sing; A Alexander-Katz; R R Netz
Journal:  Eur Phys J E Soft Matter       Date:  2011-12-14       Impact factor: 1.890

2.  Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy.

Authors:  Andrea Soranno; Brigitte Buchli; Daniel Nettels; Ryan R Cheng; Sonja Müller-Späth; Shawn H Pfeil; Armin Hoffmann; Everett A Lipman; Dmitrii E Makarov; Benjamin Schuler
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-06       Impact factor: 11.205

3.  Assessment of local friction in protein folding dynamics using a helix cross-linker.

Authors:  Beatrice N Markiewicz; Hyunil Jo; Robert M Culik; William F DeGrado; Feng Gai
Journal:  J Phys Chem B       Date:  2013-11-18       Impact factor: 2.991

4.  Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations.

Authors:  Andrea Soranno; Andrea Holla; Fabian Dingfelder; Daniel Nettels; Dmitrii E Makarov; Benjamin Schuler
Journal:  Proc Natl Acad Sci U S A       Date:  2017-02-21       Impact factor: 11.205

5.  Confinement-dependent friction in peptide bundles.

Authors:  Aykut Erbaş; Roland R Netz
Journal:  Biophys J       Date:  2013-03-19       Impact factor: 4.033

6.  Optical tweezers reveal force plateau and internal friction in PEG-induced DNA condensation.

Authors:  Heikki Ojala; Gabija Ziedaite; Anders E Wallin; Dennis H Bamford; Edward Hæggström
Journal:  Eur Biophys J       Date:  2014-01-30       Impact factor: 1.733

7.  Multivalent polymers can control phase boundary, dynamics, and organization of liquid-liquid phase separation.

Authors:  Emiko Zumbro; Alfredo Alexander-Katz
Journal:  PLoS One       Date:  2021-11-08       Impact factor: 3.240
  7 in total

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