Literature DB >> 19654385

Asthma and posttraumatic stress symptoms 5 to 6 years following exposure to the World Trade Center terrorist attack.

Robert M Brackbill1, James L Hadler, Laura DiGrande, Christine C Ekenga, Mark R Farfel, Stephen Friedman, Sharon E Perlman, Steven D Stellman, Deborah J Walker, David Wu, Shengchao Yu, Lorna E Thorpe.   

Abstract

CONTEXT: The World Trade Center Health Registry provides a unique opportunity to examine long-term health effects of a large-scale disaster.
OBJECTIVE: To examine risk factors for new asthma diagnoses and event-related posttraumatic stress (PTS) symptoms among exposed adults 5 to 6 years following exposure to the September 11, 2001, World Trade Center (WTC) terrorist attack. DESIGN, SETTING, AND PARTICIPANTS: Longitudinal cohort study with wave 1 (W1) enrollment of 71,437 adults in 2003-2004, including rescue/recovery worker, lower Manhattan resident, lower Manhattan office worker, and passersby eligibility groups; 46,322 adults (68%) completed the wave 2 (W2) survey in 2006-2007. MAIN OUTCOME MEASURES: Self-reported diagnosed asthma following September 11; event-related current PTS symptoms indicative of probable posttraumatic stress disorder (PTSD), assessed using the PTSD Checklist (cutoff score > or = 44).
RESULTS: Of W2 participants with no stated asthma history, 10.2% (95% confidence interval [CI], 9.9%-10.5%) reported new asthma diagnoses postevent. Intense dust cloud exposure on September 11 was a major contributor to new asthma diagnoses for all eligibility groups: for example, 19.1% vs 9.6% in those without exposure among rescue/recovery workers (adjusted odds ratio, 1.5 [95% CI, 1.4-1.7]). Asthma risk was highest among rescue/recovery workers on the WTC pile on September 11 (20.5% [95% CI, 19.0%-22.0%]). Persistent risks included working longer at the WTC site, not evacuating homes, and experiencing a heavy layer of dust in home or office. Of participants with no PTSD history, 23.8% (95% CI, 23.4%-24.2%) reported PTS symptoms at either W1 (14.3%) or W2 (19.1%). Nearly 10% (9.6% [95% CI, 9.3%-9.8%]) had PTS symptoms at both surveys, 4.7% (95% CI, 4.5%-4.9%) had PTS symptoms at W1 only, and 9.5% (95% CI, 9.3%-9.8%) had PTS symptoms at W2 only. At W2, passersby had the highest rate of PTS symptoms (23.2% [95% CI, 21.4%-25.0%]). Event-related loss of spouse or job was associated with PTS symptoms at W2.
CONCLUSION: Acute and prolonged exposures were both associated with a large burden of asthma and PTS symptoms 5 to 6 years after the September 11 WTC attack.

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Year:  2009        PMID: 19654385     DOI: 10.1001/jama.2009.1121

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  109 in total

1.  Chronic and acute exposures to the world trade center disaster and lower respiratory symptoms: area residents and workers.

Authors:  Carey B Maslow; Stephen M Friedman; Parul S Pillai; Joan Reibman; Kenneth I Berger; Roberta Goldring; Steven D Stellman; Mark Farfel
Journal:  Am J Public Health       Date:  2012-04-19       Impact factor: 9.308

2.  Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust.

Authors:  Shang Wang; Colette Prophete; Joleen M Soukup; Lung-Chi Chen; Max Costa; Andrew Ghio; Qingshan Qu; Mitchell D Cohen; Haobin Chen
Journal:  J Immunotoxicol       Date:  2010-08-24       Impact factor: 3.000

3.  Occupational rhinosinusitis and upper airway disease: the world trade center experience.

Authors:  Rafael E de la Hoz; Michael R Shohet; Jeffrey M Cohen
Journal:  Curr Allergy Asthma Rep       Date:  2010-03       Impact factor: 4.806

4.  Trends of elevated PTSD risk in firefighters exposed to the World Trade Center disaster: 2001-2005.

Authors:  Amy Berninger; Mayris P Webber; Hillel W Cohen; Jackson Gustave; Roy Lee; Justin K Niles; Sydney Chiu; Rachel Zeig-Owens; Jackie Soo; Kerry Kelly; David J Prezant
Journal:  Public Health Rep       Date:  2010 Jul-Aug       Impact factor: 2.792

5.  Obstructive Sleep Apnea in Community Members Exposed to World Trade Center Dust and Fumes.

Authors:  Shilpi Ahuja; Zhaoyin Zhu; Yongzhao Shao; Kenneth I Berger; Joan Reibman; Omer Ahmed
Journal:  J Clin Sleep Med       Date:  2018-05-15       Impact factor: 4.062

6.  Mental health, long-term medication adherence, and the control of asthma symptoms among persons exposed to the WTC 9/11 disaster.

Authors:  Jennifer Brite; Stephen Friedman; Rafael E de la Hoz; Joan Reibman; James Cone
Journal:  J Asthma       Date:  2019-10-10       Impact factor: 2.515

7.  Chronic physical health consequences of being injured during the terrorist attacks on World Trade Center on September 11, 2001.

Authors:  Robert M Brackbill; James E Cone; Mark R Farfel; Steven D Stellman
Journal:  Am J Epidemiol       Date:  2014-02-20       Impact factor: 4.897

Review 8.  Health effects of World Trade Center (WTC) Dust: An unprecedented disaster's inadequate risk management.

Authors:  Morton Lippmann; Mitchell D Cohen; Lung-Chi Chen
Journal:  Crit Rev Toxicol       Date:  2015-07       Impact factor: 5.635

9.  Recovery from DSM-IV post-traumatic stress disorder in the WHO World Mental Health surveys.

Authors:  A J Rosellini; H Liu; M V Petukhova; N A Sampson; S Aguilar-Gaxiola; J Alonso; G Borges; R Bruffaerts; E J Bromet; G de Girolamo; P de Jonge; J Fayyad; S Florescu; O Gureje; J M Haro; H Hinkov; E G Karam; N Kawakami; K C Koenen; S Lee; J P Lépine; D Levinson; F Navarro-Mateu; B D Oladeji; S O'Neill; B-E Pennell; M Piazza; J Posada-Villa; K M Scott; D J Stein; Y Torres; M C Viana; A M Zaslavsky; R C Kessler
Journal:  Psychol Med       Date:  2017-07-19       Impact factor: 7.723

10.  Chemosensory loss: functional consequences of the world trade center disaster.

Authors:  Pamela H Dalton; Richard E Opiekun; Michele Gould; Ryan McDermott; Tamika Wilson; Christopher Maute; Mehmet H Ozdener; Kai Zhao; Edward Emmett; Peter S J Lees; Robin Herbert; Jacqueline Moline
Journal:  Environ Health Perspect       Date:  2010-05-13       Impact factor: 9.031

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