Literature DB >> 1963948

Sequencing and expression of aadA, bla, and tnpR from the multiresistance transposon Tn1331.

M E Tolmasky1.   

Abstract

A fragment of Tn1331 including tnpR, aac, aadA, and a bla gene which encodes lower levels of resistance to ampicillin and carbenicillin as compared to those mediated by the TEM beta-lactamase was sequenced. The polypeptide encoded by the bla gene has homology with the OXA-1, PSE-2, and OXA-2 proteins. Genes aac and bla are upstream and downstream respectively of aadA, and are both flanked by recombinational hot spots. Tn1331 has 520-bp direct repeats which include parts of the tnpR and TEM bla genes. Evolutionary models for the genesis of Tn1331 are proposed.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 1963948     DOI： 10.1016/0147-619x(90)90005-w

Source DB:  PubMed          Journal:  Plasmid        ISSN： 0147-619X            Impact factor:   3.466


  29 in total

1.  A new example of physical linkage between Tn1 and Tn21: the antibiotic multiple-resistance region of plasmid pCFF04 encoding extended-spectrum beta-lactamase TEM-3.

Authors:  C Mabilat; J Lourençao-Vital; S Goussard; P Courvalin
Journal:  Mol Gen Genet       Date:  1992-10

2.  Nosocomial spread of an amikacin resistance gene on both a mobilized, nonconjugative plasmid and a conjugative plasmid.

Authors:  J D Hopkins; A Flores; M del Pilar Pla; S Lester; T F O'Brien
Journal:  Antimicrob Agents Chemother       Date:  1991-08       Impact factor: 5.191

3.  Class II transposon-borne structure harboring metallo-beta-lactamase gene blaVIM-2 in Pseudomonas putida.

Authors:  Laurent Poirel; Ludovic Cabanne; Louis Collet; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2006-08       Impact factor: 5.191

4.  Characterization of Tn6238 with a new allele of aac(6')-Ib-cr.

Authors:  María P Quiroga; Betina Orman; Laura Errecalde; Sara Kaufman; Daniela Centrón
Journal:  Antimicrob Agents Chemother       Date:  2015-02-17       Impact factor: 5.191

5.  Incidence and characterization of integrons, genetic elements mediating multiple-drug resistance, in avian Escherichia coli.

Authors:  L Bass; C A Liebert; M D Lee; A O Summers; D G White; S G Thayer; J J Maurer
Journal:  Antimicrob Agents Chemother       Date:  1999-12       Impact factor: 5.191

6.  Molecular characterization of the OXA-7 beta-lactamase gene.

Authors:  E Scoulica; A Aransay; Y Tselentis
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

7.  Differences in resolution of mwr-containing plasmid dimers mediated by the Klebsiella pneumoniae and Escherichia coli XerC recombinases: potential implications in dissemination of antibiotic resistance genes.

Authors:  Duyen Bui; Judianne Ramiscal; Sonia Trigueros; Jason S Newmark; Albert Do; David J Sherratt; Marcelo E Tolmasky
Journal:  J Bacteriol       Date:  2006-04       Impact factor: 3.490

8.  The aminoglycoside 6'-N-acetyltransferase type Ib encoded by Tn1331 is evenly distributed within the cell's cytoplasm.

Authors:  Ken J Dery; Britta Søballe; Mavee S L Witherspoon; Duyen Bui; Robert Koch; David J Sherratt; Marcelo E Tolmasky
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

9.  PCR mapping of integrons reveals several novel combinations of resistance genes.

Authors:  C Lévesque; L Piché; C Larose; P H Roy
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

10.  Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance by antisense oligodeoxynucleotides.

Authors:  Renee Sarno; Hongphuc Ha; Natalia Weinsetel; Marcelo E Tolmasky
Journal:  Antimicrob Agents Chemother       Date:  2003-10       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.