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Literature DB >> 19639025

Life can be stressful without ATR.

Mark O'Driscoll.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2009 PMID： 19639025 DOI： 10.1038/ng0809-866

Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330

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13 in total

1. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice.

Authors: Yuxun Wang; Christopher D Putnam; Michael F Kane; Weijia Zhang; Lisa Edelmann; Robert Russell; Danaise V Carrión; Lynda Chin; Raju Kucherlapati; Richard D Kolodner; Winfried Edelmann
Journal: Nat Genet Date: 2005-06-19 Impact factor: 38.330

2. Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.

Authors: Yaroslava Ruzankina; Carolina Pinzon-Guzman; Amma Asare; Tony Ong; Laura Pontano; George Cotsarelis; Valerie P Zediak; Marielena Velez; Avinash Bhandoola; Eric J Brown
Journal: Cell Stem Cell Date: 2007-06-07 Impact factor: 24.633

3. Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.

Authors: A de Klein; M Muijtjens; R van Os; Y Verhoeven; B Smit; A M Carr; A R Lehmann; J H Hoeijmakers
Journal: Curr Biol Date: 2000-04-20 Impact factor: 10.834

4. A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

Authors: Naoko Shima; Ana Alcaraz; Ivan Liachko; Tavanna R Buske; Catherine A Andrews; Robert J Munroe; Suzanne A Hartford; Bik K Tye; John C Schimenti
Journal: Nat Genet Date: 2006-12-03 Impact factor: 38.330

5. Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway.

Authors: Gemma K Alderton; Hans Joenje; Raymonda Varon; Anders D Børglum; Penny A Jeggo; Mark O'Driscoll
Journal: Hum Mol Genet Date: 2004-10-20 Impact factor: 6.150

6. A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome.

Authors: Mark O'Driscoll; Victor L Ruiz-Perez; C Geoffrey Woods; Penny A Jeggo; Judith A Goodship
Journal: Nat Genet Date: 2003-03-17 Impact factor: 38.330

7. Chk1 is haploinsufficient for multiple functions critical to tumor suppression.

Authors: Michael H Lam; Qinghua Liu; Stephen J Elledge; Jeffrey M Rosen
Journal: Cancer Cell Date: 2004-07 Impact factor: 31.743

8. ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.

Authors: Yanan Fang; Cheng-Chung Tsao; Barbara K Goodman; Ryohei Furumai; Carlos A Tirado; Robert T Abraham; Xiao-Fan Wang
Journal: EMBO J Date: 2004-07-29 Impact factor: 11.598

9. Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.

Authors: George A Garinis; Lieneke M Uittenboogaard; Heike Stachelscheid; Maria Fousteri; Wilfred van Ijcken; Timo M Breit; Harry van Steeg; Leon H F Mullenders; Gijsbertus T J van der Horst; Jens C Brüning; Carien M Niessen; Jan H J Hoeijmakers; Björn Schumacher
Journal: Nat Cell Biol Date: 2009-04-12 Impact factor: 28.824

10. Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling.

Authors: Elen Griffith; Sarah Walker; Carol-Anne Martin; Paola Vagnarelli; Tom Stiff; Bertrand Vernay; Nouriya Al Sanna; Anand Saggar; Ben Hamel; William C Earnshaw; Penny A Jeggo; Andrew P Jackson; Mark O'Driscoll
Journal: Nat Genet Date: 2007-12-23 Impact factor: 38.330

2 in total

1. Global heterochromatin loss: a unifying theory of aging?

Authors: Amy Tsurumi; Willis X Li
Journal: Epigenetics Date: 2012-07-01 Impact factor: 4.528

Review 2. Diseases associated with defective responses to DNA damage.

Authors: Mark O'Driscoll
Journal: Cold Spring Harb Perspect Biol Date: 2012-12-01 Impact factor: 10.005

2 in total