| Literature DB >> 19638636 |
Abstract
Pediatric high-grade gliomas represent approximately 10% of all pediatric brain tumors. Similar to adult high-grade gliomas, they behave very aggressively, and these children have a very poor prognosis despite a variety of therapies that include chemotherapy and radiotherapy. In this review, we present an overview of both pediatric high-grade gliomas and diffuse intrinsic pontine gliomas with a focus on their epidemiology, etiology, presentation, prognostic factors, biology, treatment modalities, outcomes, and future research directions.Entities:
Mesh:
Year: 2009 PMID: 19638636 DOI: 10.1177/0883073809338960
Source DB: PubMed Journal: J Child Neurol ISSN: 0883-0738 Impact factor: 1.987