| Literature DB >> 19636473 |
Sang Uk Son1, Robin L Garrell.
Abstract
We demonstrate the first programmed transport of live yeast (Saccharomyces cerevisiae) and a zebrafish embryo (Danio rerio) within droplets in a two-plate digital microfluidic device. The yeast remained viable after transport, and the actuated droplets left no yeast behind. A zebrafish embryo transported 2 hours after fertilization developed normally and hatched. Dechorionation was demonstrated by mixing a droplet of digestive reagent droplet with a droplet containing the embryo. These results demonstrate the potential for using a droplet microfluidic device as an alternative to microwell plates for yeast and zebrafish assays.Entities:
Mesh:
Year: 2009 PMID: 19636473 DOI: 10.1039/b906257b
Source DB: PubMed Journal: Lab Chip ISSN: 1473-0189 Impact factor: 6.799