BACKGROUND: The aim of this study was to determine the risk factors for conversion from a normal to either a low or high ankle-brachial index (ABI). METHODS: Participants in the Multi-Ethnic Study of Atherosclerosis who had two separate measurements of the ABI over a 3-year time period were assessed. RESULTS: At baseline, the mean age was 62 years and 50% were women, 28% African American, 12% Chinese, 22% Hispanic and 38% non-Hispanic White. Of the 5514 participants with a baseline ABI between 0.90 and 1.40, 89 (1.6%) had an ABI < or = 0.90 ("low ABI group") and 71 (1.3%) had an ABI > or = 1.40 ("high ABI group") 3 years later. On multivariable analysis, the odds for having progressed into the low ABI group were significantly increased for higher baseline age, hypertension, diabetes, greater pack-years of cigarette smoking, and homocysteine levels. The odds for progression into the high ABI group were increased for male gender and higher body mass index. Compared with non-Hispanic Whites, African Americans had a significantly higher odds for progression to the low ABI group (odds ratio [OR]: 2.24, 95% confidence interval [CI]: 1.29-3.88) while having a reduced odds for progression to the high ABI group (OR: 0.50, 95% CI: 0.24-1.00). Neither Chinese nor Hispanic ethnicity was significantly associated with progression to either ABI group. CONCLUSIONS: The risk factors for progression to a low or high ABI were distinct and African Americans were at increased risk for progression to a low ABI but at decreased risk for progression into the high ABI group.
BACKGROUND: The aim of this study was to determine the risk factors for conversion from a normal to either a low or high ankle-brachial index (ABI). METHODS:Participants in the Multi-Ethnic Study of Atherosclerosis who had two separate measurements of the ABI over a 3-year time period were assessed. RESULTS: At baseline, the mean age was 62 years and 50% were women, 28% African American, 12% Chinese, 22% Hispanic and 38% non-Hispanic White. Of the 5514 participants with a baseline ABI between 0.90 and 1.40, 89 (1.6%) had an ABI < or = 0.90 ("low ABI group") and 71 (1.3%) had an ABI > or = 1.40 ("high ABI group") 3 years later. On multivariable analysis, the odds for having progressed into the low ABI group were significantly increased for higher baseline age, hypertension, diabetes, greater pack-years of cigarette smoking, and homocysteine levels. The odds for progression into the high ABI group were increased for male gender and higher body mass index. Compared with non-Hispanic Whites, African Americans had a significantly higher odds for progression to the low ABI group (odds ratio [OR]: 2.24, 95% confidence interval [CI]: 1.29-3.88) while having a reduced odds for progression to the high ABI group (OR: 0.50, 95% CI: 0.24-1.00). Neither Chinese nor Hispanic ethnicity was significantly associated with progression to either ABI group. CONCLUSIONS: The risk factors for progression to a low or high ABI were distinct and African Americans were at increased risk for progression to a low ABI but at decreased risk for progression into the high ABI group.
Authors: Victor Aboyans; Michael H Criqui; Julie O Denenberg; James D Knoke; Paul M Ridker; Arnost Fronek Journal: Circulation Date: 2006-05-30 Impact factor: 29.690
Authors: Matthew A Allison; Michael H Criqui; Robyn L McClelland; JoAnn M Scott; Mary M McDermott; Kiang Liu; Aaron R Folsom; Alain G Bertoni; A Richey Sharrett; Shunichi Homma; Sujata Kori Journal: J Am Coll Cardiol Date: 2006-08-28 Impact factor: 24.094
Authors: Matthew A Allison; Elena Ho; Julie O Denenberg; Robert D Langer; Anne B Newman; Richard R Fabsitz; Michael H Criqui Journal: Am J Prev Med Date: 2007-04 Impact factor: 5.043
Authors: Victor Aboyans; Michael H Criqui; Robyn L McClelland; Matthew A Allison; Mary McGrae McDermott; David C Goff; Teri A Manolio Journal: J Vasc Surg Date: 2007-02 Impact factor: 4.268
Authors: Matthew A Allison; William R Hiatt; Alan T Hirsch; Joseph R Coll; Michael H Criqui Journal: J Am Coll Cardiol Date: 2008-04-01 Impact factor: 24.094
Authors: Michael H Criqui; Victor Aboyans; Matthew A Allison; Julie O Denenberg; Nketi Forbang; Mary M McDermott; Christina L Wassel; Nathan D Wong Journal: Glob Heart Date: 2016-09
Authors: F Gerry R Fowkes; Victor Aboyans; Freya J I Fowkes; Mary M McDermott; Uchechukwu K A Sampson; Michael H Criqui Journal: Nat Rev Cardiol Date: 2016-11-17 Impact factor: 32.419
Authors: Matthew A Allison; Franklyn Gonzalez; Leopoldo Raij; Robert Kaplan; Robert J Ostfeld; Maria S Pattany; Gerardo Heiss; Michael H Criqui Journal: J Vasc Surg Date: 2015-07-02 Impact factor: 4.268
Authors: Nketi I Forbang; Mary M McDermott; Yihua Liao; Joachim H Ix; Matthew A Allison; Kiang Liu; Lu Tian; Natalie Evans; Michael H Criqui Journal: Vasc Med Date: 2014-10-30 Impact factor: 3.239
Authors: Monica L Bertoia; Jennifer K Pai; John P Cooke; Michel M Joosten; Murray A Mittleman; Eric B Rimm; Kenneth J Mukamal Journal: Atherosclerosis Date: 2014-04-28 Impact factor: 5.162
Authors: Raphael Mendes Ritti-Dias; Ji Li; Kimberly M Hollabaugh; Julie A Stoner; Polly S Montgomery; Andrew W Gardner Journal: J Cardiopulm Rehabil Prev Date: 2013 Nov-Dec Impact factor: 2.081
Authors: Caitlin W Hicks; Ning Ding; Lucia Kwak; Shoshana H Ballew; Corey A Kalbaugh; Aaron R Folsom; Gerardo Heiss; Josef Coresh; James H Black; Elizabeth Selvin; Kunihiro Matsushita Journal: Atherosclerosis Date: 2021-03-29 Impact factor: 5.162
Authors: Thanh-Huyen T Vu; Jeremiah Stamler; Kiang Liu; Mary M McDermott; Donald M Lloyd-Jones; Amber Pirzada; Daniel B Garside; Martha L Daviglus Journal: J Am Heart Assoc Date: 2012-12-19 Impact factor: 5.501