| Literature DB >> 19622385 |
David C Klein1, Michael J Bailey, David A Carter, Jong-so Kim, Qiong Shi, Anthony K Ho, Constance L Chik, Pascaline Gaildrat, Fabrice Morin, Surajit Ganguly, Martin F Rath, Morten Møller, David Sugden, Zoila G Rangel, Peter J Munson, Joan L Weller, Steven L Coon.
Abstract
Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function. Published by Elsevier Ireland Ltd.Entities:
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Year: 2009 PMID: 19622385 PMCID: PMC3138125 DOI: 10.1016/j.mce.2009.07.010
Source DB: PubMed Journal: Mol Cell Endocrinol ISSN: 0303-7207 Impact factor: 4.102