Literature DB >> 19607875

Construction of a DNA nano-object directly demonstrates computation.

Gang Wu1, Natasha Jonoska, Nadrian C Seeman.   

Abstract

We demonstrate a computing method in which a DNA nano-object representing the solution of a problem emerges as a result of self-assembly. We report an experiment in which three-vertex colorability for a six-vertex graph with nine edges is solved by constructing a DNA molecule representing the colored graph itself. Our findings show that computation based on "shape processing" is a viable alternative to symbol processing when computing by molecular self-assembly.

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Year:  2009        PMID: 19607875      PMCID: PMC2763046          DOI: 10.1016/j.biosystems.2009.07.004

Source DB:  PubMed          Journal:  Biosystems        ISSN: 0303-2647            Impact factor:   1.973


  12 in total

1.  Molecular computation: RNA solutions to chess problems.

Authors:  D Faulhammer; A R Cukras; R J Lipton; L F Landweber
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-15       Impact factor: 11.205

2.  Logical computation using algorithmic self-assembly of DNA triple-crossover molecules.

Authors:  C Mao; T H LaBean; J H Relf; N C Seeman
Journal:  Nature       Date:  2000-09-28       Impact factor: 49.962

3.  Self-assembly of irregular graphs whose edges are DNA helix axes.

Authors:  Phiset Sa-Ardyen; Natasha Jonoska; Nadrian C Seeman
Journal:  J Am Chem Soc       Date:  2004-06-02       Impact factor: 15.419

4.  Architecture with GIDEON, a program for design in structural DNA nanotechnology.

Authors:  Jeffrey J Birac; William B Sherman; Jens Kopatsch; Pamela E Constantinou; Nadrian C Seeman
Journal:  J Mol Graph Model       Date:  2006-04-19       Impact factor: 2.518

5.  DNA solution of the maximal clique problem.

Authors:  Q Ouyang; P D Kaplan; S Liu; A Libchaber
Journal:  Science       Date:  1997-10-17       Impact factor: 47.728

6.  On existence of reporter strands in DNA-based graph structures.

Authors:  Nataša Jonoska; Nadrian C Seeman; Gang Wu
Journal:  Theor Comput Sci       Date:  2008-12-11       Impact factor: 0.827

7.  DNA solution of hard computational problems.

Authors:  R J Lipton
Journal:  Science       Date:  1995-04-28       Impact factor: 47.728

8.  Molecular computation of solutions to combinatorial problems.

Authors:  L M Adleman
Journal:  Science       Date:  1994-11-11       Impact factor: 47.728

9.  Nucleic acid junctions and lattices.

Authors:  N C Seeman
Journal:  J Theor Biol       Date:  1982-11-21       Impact factor: 2.691

10.  2',2'-Ligation Demonstrates the Thermal Dependence of DNA-Directed Positional Control.

Authors:  Yu Liu; Ruojie Sha; Risheng Wang; Liang Ding; James W Canary; Nadrian C Seeman
Journal:  Tetrahedron       Date:  2008-01       Impact factor: 2.457

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  5 in total

1.  Training a molecular automaton to play a game.

Authors:  Renjun Pei; Elizabeth Matamoros; Manhong Liu; Darko Stefanovic; Milan N Stojanovic
Journal:  Nat Nanotechnol       Date:  2010-10-24       Impact factor: 39.213

2.  Computing by molecular self-assembly.

Authors:  Nataša Jonoska; Nadrian C Seeman
Journal:  Interface Focus       Date:  2012-02-08       Impact factor: 3.906

3.  Bending of short DNA helices.

Authors:  Alexander Vologodskii; Quan Du; Maxim D Frank-Kamenetskii
Journal:  Artif DNA PNA XNA       Date:  2013-01-01

4.  Self-assembled DNA crystals: the impact on resolution of 5'-phosphates and the DNA source.

Authors:  Ruojie Sha; Jens J Birktoft; Nam Nguyen; Arun Richard Chandrasekaran; Jianping Zheng; Xinshuai Zhao; Chengde Mao; Nadrian C Seeman
Journal:  Nano Lett       Date:  2013-01-22       Impact factor: 11.189

Review 5.  Strong bending of the DNA double helix.

Authors:  Alexander Vologodskii; Maxim D Frank-Kamenetskii
Journal:  Nucleic Acids Res       Date:  2013-05-15       Impact factor: 16.971

  5 in total

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