| Literature DB >> 19606814 |
Carolina Gella1, Eric Ferrer, Ramon Alibés, Félíx Busqué, Pedro de March, Marta Figueredo, Josep Font.
Abstract
An efficient and metal-free protocol for direct oxidation of secondary amines to nitrones has been developed, using Oxone in a biphasic basic medium as the sole oxidant. The method is general and tolerant with other functional groups or existing stereogenic centers, providing rapid access to enantiomerically pure compounds in good yields.Entities:
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Year: 2009 PMID： 19606814 DOI： 10.1021/jo901108u
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354