Literature DB >> 19606132

Ageing: A midlife longevity drug?

Matt Kaeberlein, Brian K Kennedy.   

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Year:  2009        PMID： 19606132     DOI： 10.1038/460331a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  9 in total

1.  Genetics: influence of TOR kinase on lifespan in C. elegans.

Authors:  Tibor Vellai; Krisztina Takacs-Vellai; Yue Zhang; Attila L Kovacs; László Orosz; Fritz Müller
Journal:  Nature       Date:  2003-12-11       Impact factor: 49.962

2.  Extension of chronological life span in yeast by decreased TOR pathway signaling.

Authors:  R Wilson Powers; Matt Kaeberlein; Seth D Caldwell; Brian K Kennedy; Stanley Fields
Journal:  Genes Dev       Date:  2006-01-15       Impact factor: 11.361

3.  Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.

Authors:  Matt Kaeberlein; R Wilson Powers; Kristan K Steffen; Eric A Westman; Di Hu; Nick Dang; Emily O Kerr; Kathryn T Kirkland; Stanley Fields; Brian K Kennedy
Journal:  Science       Date:  2005-11-18       Impact factor: 47.728

4.  The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span.

Authors:  Kailiang Jia; Di Chen; Donald L Riddle
Journal:  Development       Date:  2004-07-14       Impact factor: 6.868

5.  Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.

Authors:  Erica D Smith; Mitsuhiro Tsuchiya; Lindsay A Fox; Nick Dang; Di Hu; Emily O Kerr; Elijah D Johnston; Bie N Tchao; Diana N Pak; K Linnea Welton; Daniel E L Promislow; James H Thomas; Matt Kaeberlein; Brian K Kennedy
Journal:  Genome Res       Date:  2008-03-13       Impact factor: 9.043

6.  Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

Authors:  Kristan K Steffen; Vivian L MacKay; Emily O Kerr; Mitsuhiro Tsuchiya; Di Hu; Lindsay A Fox; Nick Dang; Elijah D Johnston; Jonathan A Oakes; Bie N Tchao; Diana N Pak; Stanley Fields; Brian K Kennedy; Matt Kaeberlein
Journal:  Cell       Date:  2008-04-18       Impact factor: 41.582

7.  Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway.

Authors:  Pankaj Kapahi; Brian M Zid; Tony Harper; Daniel Koslover; Viveca Sapin; Seymour Benzer
Journal:  Curr Biol       Date:  2004-05-25       Impact factor: 10.834

8.  Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.

Authors:  David E Harrison; Randy Strong; Zelton Dave Sharp; James F Nelson; Clinton M Astle; Kevin Flurkey; Nancy L Nadon; J Erby Wilkinson; Krystyna Frenkel; Christy S Carter; Marco Pahor; Martin A Javors; Elizabeth Fernandez; Richard A Miller
Journal:  Nature       Date:  2009-07-08       Impact factor: 49.962

9.  A role for autophagy in the extension of lifespan by dietary restriction in C. elegans.

Authors:  Malene Hansen; Abha Chandra; Laura L Mitic; Brian Onken; Monica Driscoll; Cynthia Kenyon
Journal:  PLoS Genet       Date:  2008-02       Impact factor: 5.917
  9 in total
  28 in total

1.  Listening to public concerns about human life extension. The public view of life-extension technologies is more nuanced than expected and researchers must engage in discussions if they hope to promote awareness and acceptance.

Authors:  Brad Partridge; Jayne Lucke; Wayne Hall
Journal:  EMBO Rep       Date:  2010-09-10       Impact factor: 8.807

2.  Hot topics in aging research: protein translation and TOR signaling, 2010.

Authors:  Matt Kaeberlein; Brian K Kennedy
Journal:  Aging Cell       Date:  2011-01-20       Impact factor: 9.304

3.  Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.

Authors:  Richard A Miller; David E Harrison; C M Astle; Joseph A Baur; Angela Rodriguez Boyd; Rafael de Cabo; Elizabeth Fernandez; Kevin Flurkey; Martin A Javors; James F Nelson; Carlos J Orihuela; Scott Pletcher; Zelton Dave Sharp; David Sinclair; Joseph W Starnes; J Erby Wilkinson; Nancy L Nadon; Randy Strong
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2010-10-25       Impact factor: 6.053

4.  Spermidine surprise for a long life.

Authors:  Matt Kaeberlein
Journal:  Nat Cell Biol       Date:  2009-11       Impact factor: 28.824

5.  Fasting levels of hepatic p-S6 are increased in old mice.

Authors:  Olga V Leontieva; Geraldine M Paszkiewicz; Mikhail V Blagosklonny
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

6.  NIA's Intervention Testing Program at 10 years of age.

Authors:  Huber R Warner
Journal:  Age (Dordr)       Date:  2015-03-01

Review 7.  The Biology of Aging: Citizen Scientists and Their Pets as a Bridge Between Research on Model Organisms and Human Subjects.

Authors:  M Kaeberlein
Journal:  Vet Pathol       Date:  2015-06-15       Impact factor: 2.221

8.  Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

Authors:  Olga V Leontieva; Venkatesh Natarajan; Zoya N Demidenko; Lyudmila G Burdelya; Andrei V Gudkov; Mikhail V Blagosklonny
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-30       Impact factor: 11.205

9.  Sexes suffer from suboptimal lifespan because of genetic conflict in a seed beetle.

Authors:  Elena C Berg; Alexei A Maklakov
Journal:  Proc Biol Sci       Date:  2012-08-22       Impact factor: 5.349

10.  Hypoxia and gerosuppression: the mTOR saga continues.

Authors:  Olga V Leontieva; Mikhail V Blagosklonny
Journal:  Cell Cycle       Date:  2012-09-17       Impact factor: 4.534
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