Literature DB >> 19604526

Cytotoxic 16-beta-[(D-xylopyranosyl)oxy]oxohexadecanyl triterpene glycosides from a Malagasy plant, Physena sessiliflora.

Masaki Inoue1, Kazuhiro Ohtani2, Ryoji Kasai2, Mayu Okukubo2, Marta Andriantsiferana3, Kazuo Yamasaki2, Tohru Koike2.   

Abstract

Brine shrimp lethality assay-guided separation of the MeOH extract of leaves of Physena sessiliflora, which is endemic to Madagascar, afforded eight triterpene glycosides, Physenoside S1-4 and 16-beta-[(d-xylopyranosyl)oxy]oxohexadecanyl homologues, Physenoside S5-8. Structural elucidation of these compounds was based on both spectroscopic analyses and chemical properties. Physenoside S7 and S8 have significant cytotoxic activities in the brine shrimp lethality assay.

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Year:  2009        PMID: 19604526     DOI: 10.1016/j.phytochem.2009.06.002

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  2 in total

1.  Saponins as cytotoxic agents: a review.

Authors:  Irma Podolak; Agnieszka Galanty; Danuta Sobolewska
Journal:  Phytochem Rev       Date:  2010-06-25       Impact factor: 5.374

2.  Tirucallane Triterpenoids from the Stems and Stem Bark of Cornus walteri that Control Adipocyte and Osteoblast Differentiations.

Authors:  Seoung Rak Lee; Eunyong Choi; Se Hun Jeon; Xue Yan Zhi; Jae Sik Yu; Seon-Hee Kim; Jeongmi Lee; Ki-Moon Park; Ki Hyun Kim
Journal:  Molecules       Date:  2018-10-23       Impact factor: 4.411

  2 in total

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