Literature DB >> 19603110

Mirror image phage display--a method to generate D-peptide ligands for use in diagnostic or therapeutical applications.

Susanne Aileen Funke1, Dieter Willbold.   

Abstract

Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.

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Year:  2009        PMID： 19603110     DOI： 10.1039/b904138a

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  24 in total

Review 1.  Novel protein science enabled by total chemical synthesis.

Authors:  Stephen B H Kent
Journal:  Protein Sci       Date:  2018-12-18       Impact factor: 6.725

2.  Total Chemical Synthesis and Folding of All-l and All-d Variants of Oncogenic KRas(G12V).

Authors:  Adam M Levinson; John H McGee; Andrew G Roberts; Gardner S Creech; Ting Wang; Michael T Peterson; Ronald C Hendrickson; Gregory L Verdine; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2017-05-22       Impact factor: 15.419

Review 3.  Smart self-assembled hybrid hydrogel biomaterials.

Authors:  Jindřich Kopeček; Jiyuan Yang
Journal:  Angew Chem Int Ed Engl       Date:  2012-07-23       Impact factor: 15.336

4.  Nature versus design: the conformational propensities of D-amino acids and the importance of side chain chirality.

Authors:  Clare-Louise Towse; Gene Hopping; Ivan Vulovic; Valerie Daggett
Journal:  Protein Eng Des Sel       Date:  2014-09-18       Impact factor: 1.650

5.  Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography.

Authors:  Kalyaneswar Mandal; Maruti Uppalapati; Dana Ault-Riché; John Kenney; Joshua Lowitz; Sachdev S Sidhu; Stephen B H Kent
Journal:  Proc Natl Acad Sci U S A       Date:  2012-08-27       Impact factor: 11.205

Review 6.  Peptides for therapy and diagnosis of Alzheimer's disease.

Authors:  Susanne Aileen Funke; Dieter Willbold
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

Review 7.  Structural Studies Providing Insights into Production and Conformational Behavior of Amyloid-β Peptide Associated with Alzheimer's Disease Development.

Authors:  Anatoly S Urban; Konstantin V Pavlov; Anna V Kamynina; Ivan S Okhrimenko; Alexander S Arseniev; Eduard V Bocharov
Journal:  Molecules       Date:  2021-05-13       Impact factor: 4.411

Review 8.  Discovery of Antivirals Using Phage Display.

Authors:  Esen Sokullu; Marie-Soleil Gauthier; Benoit Coulombe
Journal:  Viruses       Date:  2021-06-10       Impact factor: 5.048

9.  SwissSidechain: a molecular and structural database of non-natural sidechains.

Authors:  David Gfeller; Olivier Michielin; Vincent Zoete
Journal:  Nucleic Acids Res       Date:  2012-10-26       Impact factor: 16.971

Review 10.  NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications.

Authors:  Chenyang Jiang; Haojie Huang; Xueying Kang; Liu Yang; Zhen Xi; Hongyan Sun; Michael D Pluth; Long Yi
Journal:  Chem Soc Rev       Date:  2021-07-05       Impact factor: 60.615
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