Literature DB >> 19601577

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.

Yu Yu1, Danuta S Kalinowski, Zaklina Kovacevic, Aritee R Siafakas, Patric J Jansson, Christian Stefani, David B Lovejoy, Philip C Sharpe, Paul V Bernhardt, Des R Richardson.   

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Year:  2009        PMID： 19601577     DOI： 10.1021/jm900552r

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  86 in total

1.  Allele-specific p53 mutant reactivation.

Authors:  Xin Yu; Alexei Vazquez; Arnold J Levine; Darren R Carpizo
Journal:  Cancer Cell       Date:  2012-05-15       Impact factor: 31.743

2.  A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo.

Authors:  Chad N Hancock; Luke H Stockwin; Bingnan Han; Raymond D Divelbiss; Jung Ho Jun; Sanjay V Malhotra; Melinda G Hollingshead; Dianne L Newton
Journal:  Free Radic Biol Med       Date:  2010-11-04       Impact factor: 7.376

3.  Biological assays and noncovalent interactions of pyridine-2-carbaldehyde thiosemicarbazonecopper(II) drugs with [poly(dA-dT)](2), [poly(dG-dC)] (2), and calf thymus DNA.

Authors:  Rebeca Ruiz; Begoña García; Javier Garcia-Tojal; Natalia Busto; Saturnino Ibeas; José M Leal; Célia Martins; Jorge Gaspar; Joaquín Borrás; Rubén Gil-García; Marta González-Alvarez
Journal:  J Biol Inorg Chem       Date:  2010-01-20       Impact factor: 3.358

4.  Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models.

Authors:  Moses Q Wilks; Marc D Normandin; Hushan Yuan; Hoonsung Cho; Yanyan Guo; Fanny Herisson; Cenk Ayata; Dustin W Wooten; Georges El Fakhri; Lee Josephson
Journal:  Bioconjug Chem       Date:  2015-05-14       Impact factor: 4.774

5.  A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα.

Authors:  Shayna Sandhaus; Rosella Taylor; Tiffany Edwards; Alexis Huddleston; Ykeysha Wooten; Ramaiyer Venkatraman; Ralph T Weber; Antonio González-Sarrías; Patrick M Martin; Patrice Cagle; Yuk-Ching Tse-Dinh; Stephen J Beebe; Navindra Seeram; Alvin A Holder
Journal:  Inorg Chem Commun       Date:  2016-02       Impact factor: 2.495

Review 6.  Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 1.

Authors:  Hui-Ming Chang; Rohit Moudgil; Tiziano Scarabelli; Tochukwu M Okwuosa; Edward T H Yeh
Journal:  J Am Coll Cardiol       Date:  2017-11-14       Impact factor: 24.094

7.  Targeting Iron in Colon Cancer via Glycoconjugation of Thiosemicarbazone Prochelators.

Authors:  Eman A Akam; Elisa Tomat
Journal:  Bioconjug Chem       Date:  2016-07-29       Impact factor: 4.774

Review 8.  Pharmacology of iron transport.

Authors:  Shaina L Byrne; Divya Krishnamurthy; Marianne Wessling-Resnick
Journal:  Annu Rev Pharmacol Toxicol       Date:  2012-09-27       Impact factor: 13.820

Review 9.  Iron-targeting antitumor activity of gallium compounds and novel insights into triapine(®)-metal complexes.

Authors:  Christopher R Chitambar; William E Antholine
Journal:  Antioxid Redox Signal       Date:  2012-10-03       Impact factor: 8.401

10.  Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping.

Authors:  Judith M Myers; Qing Cheng; William E Antholine; Balaraman Kalyanaraman; Aleksandra Filipovska; Elias S J Arnér; Charles R Myers
Journal:  Free Radic Biol Med       Date:  2013-02-26       Impact factor: 7.376
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