| Literature DB >> 19598010 |
Yuanyuan Zhang1, Junming Guo, Dong Li, Bingxiu Xiao, Ying Miao, Zhen Jiang, Hui Zhuo.
Abstract
MicroRNAs (miRNAs) are non-coding RNAs that regulate the expression of target mRNAs. Altered expression of specific miRNAs in several tumor types has been reported. However, the expression levels of miR-31 in gastric cancers are unclear. The objective of the present study was to compare the expression profile of miR-31 between gastric cancer tissues and non-tumor tissues. Real-time quantitative reverse transcription-polymerase chain reaction technology was used to detect the levels of miR-31 expression. The expression levels of miR-31 in gastric cancer tissues were significantly lower than those in non-tumor tissues. This new information may help to clarify the molecular mechanisms involved in gastric carcinogenesis and to indicate that miR-31 may be a novel diagnostic biomarker of gastric cancer.Entities:
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Year: 2009 PMID： 19598010 DOI： 10.1007/s12032-009-9269-x
Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064