Literature DB >> 19596461

Digital pathology in drug discovery and development: multisite integration.

Steven J Potts1.   

Abstract

Digital pathology is an emerging technology that provides an image-based environment for managing and interpreting the information generated from a digitized glass slide, offering substantial improvements in pharmaceutical drug development across discovery, preclinical GLP pathology and oncology clinical trials. Digital pathology is transforming global pharmaceutical research by enabling data sharing to integrate dispersed pharma pathology labs around the world. This article reviews the stages of multisite digital pathology integration in large pharmaceutical companies, offering suggestions for success and highlighting challenges.

Mesh：

Year:  2009        PMID： 19596461     DOI： 10.1016/j.drudis.2009.06.013

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  7 in total

Review 1.  The Empirical Foundations of Telepathology: Evidence of Feasibility and Intermediate Effects.

Authors:  Rashid L Bashshur; Elizabeth A Krupinski; Ronald S Weinstein; Matthew R Dunn; Noura Bashshur
Journal:  Telemed J E Health       Date:  2017-02-07       Impact factor: 3.536

2.  Sclerosing Sialadenitis Is Associated With Salivary Gland Hypofunction and a Unique Gene Expression Profile in Sjögren's Syndrome.

Authors:  Hongen Yin; Thomas J F Pranzatelli; Benjamin N French; Nan Zhang; Blake M Warner; John A Chiorini
Journal:  Front Immunol       Date:  2021-07-30       Impact factor: 7.561

3.  A flexible, open, decentralized system for digital pathology networks.

Authors:  Robert Schuler; David E Smith; Gowri Kumaraguruparan; Ann Chervenak; Anne D Lewis; Dallas M Hyde; Carl Kesselman
Journal:  Stud Health Technol Inform       Date:  2012

Review 4.  Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice.

Authors:  Paul N Schofield; Peter Vogel; Georgios V Gkoutos; John P Sundberg
Journal:  Dis Model Mech       Date:  2011-10-25       Impact factor: 5.758

5.  Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model of Cancer.

Authors:  Jessica Kalra; Weislawa H Dragowska; Marcel B Bally
Journal:  J Histochem Cytochem       Date:  2015-05-04       Impact factor: 2.479

6.  Quantitative analysis of histopathological findings using image processing software.

Authors:  Yasushi Horai; Tetsuhiro Kakimoto; Kana Takemoto; Masaharu Tanaka
Journal:  J Toxicol Pathol       Date:  2017-08-20       Impact factor: 1.628

Review 7.  Digital pathology and artificial intelligence in translational medicine and clinical practice.

Authors:  Vipul Baxi; Robin Edwards; Michael Montalto; Saurabh Saha
Journal:  Mod Pathol       Date:  2021-10-05       Impact factor: 7.842
  7 in total

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