| Literature DB >> 19591453 |
On-Yi Lee1, Ka-Lun Law, Dan Yang.
Abstract
A robust and reliable method has been developed for reductive amination of primary amines with various aldehydes and ketones using Zn(ClO(4))(2) x 6 H(2)O as a catalyst. [In-H] generated in situ via a combination of InCl(3) and Et(3)SiH is employed as an effective reducing system. A variety of secondary amines can be synthesized in a one-pot procedure in excellent yields.Entities:
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Year: 2009 PMID： 19591453 DOI： 10.1021/ol901111g
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005