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Literature DB >> 19590528

Activated Ras signaling significantly enhances reovirus replication and spread.

M Shmulevitz, P Marcato, P W K Lee.

Abstract

Entities: Species

Mesh：

Substances：
ras Proteins

Year: 2010 PMID： 19590528 DOI： 10.1038/cgt.2009.46

Source DB: PubMed Journal: Cancer Gene Ther ISSN： 0929-1903 Impact factor: 5.987

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12 in total

1. The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status.

Authors: M Kim; C T Williamson; J Prudhomme; D G Bebb; K Riabowol; P W K Lee; S P Lees-Miller; Y Mori; M M Rahman; G McFadden; R N Johnston
Journal: Oncogene Date: 2010-05-17 Impact factor: 9.867

2. Reduction of virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation toward tumorigenic cells.

Authors: Adil Mohamed; Carmit Teicher; Sarah Haefliger; Maya Shmulevitz
Journal: J Virol Date: 2015-02-04 Impact factor: 5.103

3. Oncolytic virus-initiated protective immunity against prostate cancer.

Authors: Shashi A Gujar; D A Pan; Paola Marcato; Katy A Garant; Patrick W K Lee
Journal: Mol Ther Date: 2011-01-18 Impact factor: 11.454

4. Single Amino Acid Differences between Closely Related Reovirus T3D Lab Strains Alter Oncolytic Potency In Vitro and In Vivo.

Authors: Adil Mohamed; Derek R Clements; Shashi A Gujar; Patrick W Lee; James R Smiley; Maya Shmulevitz
Journal: J Virol Date: 2020-01-31 Impact factor: 5.103

Activated Ras signaling significantly enhances reovirus replication and spread.

1. The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status.

2. Reduction of virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation toward tumorigenic cells.

3. Oncolytic virus-initiated protective immunity against prostate cancer.

4. Single Amino Acid Differences between Closely Related Reovirus T3D Lab Strains Alter Oncolytic Potency In Vitro and In Vivo.

5. Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma.

Review 6. Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment.

7. The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis.

8. Altered Hepa1-6 cells by dimethyl sulfoxide (DMSO)-treatment induce anti-tumor immunity in vivo.

Review 9. Reovirus in cancer therapy: an evidence-based review.

Review 10. Role of MAPK/MNK1 signaling in virus replication.