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Literature DB >> 19587760

Synthesis at the molecular frontier.

Paul A Wender¹, Benjamin L Miller.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19587760 PMCID： PMC2857510 DOI： 10.1038/460197a

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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36 in total

Review 1. Target-oriented and diversity-oriented organic synthesis in drug discovery.

Authors: S L Schreiber
Journal: Science Date: 2000-03-17 Impact factor: 47.728

2. Bacteriorhodopsin as a Photochromic Retinal Protein for Optical Memories.

Authors: Norbert Hampp
Journal: Chem Rev Date: 2000-05-10 Impact factor: 60.622

3. Introduction: Frontiers in Organic Synthesis.

Authors: Paul A. Wender
Journal: Chem Rev Date: 1996-02-01 Impact factor: 60.622

Review 4. The chemistry and biology of the bryostatin antitumour macrolides.

Authors: Karl J Hale; Marc G Hummersone; Soraya Manaviazar; Mark Frigerio
Journal: Nat Prod Rep Date: 2002-08 Impact factor: 13.423

Review 5. A case study in biomimetic total synthesis: polyolefin carbocyclizations to terpenes and steroids.

Authors: Ryan A Yoder; Jeffrey N Johnston
Journal: Chem Rev Date: 2005-12 Impact factor: 60.622

6. Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina.

Authors: Sebastian Sudek; Nicole B Lopanik; Laura E Waggoner; Mark Hildebrand; Christine Anderson; Haibin Liu; Amrish Patel; David H Sherman; Margo G Haygood
Journal: J Nat Prod Date: 2007-01 Impact factor: 4.050

7. A stereoselective synthesis of (-)-tetrodotoxin.

Authors: Andrew Hinman; J Du Bois
Journal: J Am Chem Soc Date: 2003-09-24 Impact factor: 15.419

Review 8. Biosynthesis of aromatic polyketides in bacteria.

Authors: Abhirup Das; Chaitan Khosla
Journal: Acc Chem Res Date: 2009-05-19 Impact factor: 22.384

Review 9. Function-oriented synthesis, step economy, and drug design.

Authors: Paul A Wender; Vishal A Verma; Thomas J Paxton; Thomas H Pillow
Journal: Acc Chem Res Date: 2007-12-27 Impact factor: 22.384

Review 10. Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic sets.

Authors: Andrew T Krueger; Eric T Kool
Journal: Chem Biol Date: 2009-03-27

72 in total

1. Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis.

Authors: Paul A Wender; Brian A Loy; Adam J Schrier
Journal: Isr J Chem Date: 2011-03-24 Impact factor: 3.333

2. Rapid and stereochemically flexible synthesis of polypropionates: super-silyl-governed aldol cascades.

Authors: Patrick B Brady; Hisashi Yamamoto
Journal: Angew Chem Int Ed Engl Date: 2012-01-17 Impact factor: 15.336

3. Strategies for recognition of stem-loop RNA structures by synthetic ligands: application to the HIV-1 frameshift stimulatory sequence.

Authors: Prakash B Palde; Leslie O Ofori; Peter C Gareiss; Jaclyn Lerea; Benjamin L Miller
Journal: J Med Chem Date: 2010-08-26 Impact factor: 7.446

Synthesis at the molecular frontier.

Review 1. Target-oriented and diversity-oriented organic synthesis in drug discovery.

2. Bacteriorhodopsin as a Photochromic Retinal Protein for Optical Memories.

3. Introduction: Frontiers in Organic Synthesis.

Review 4. The chemistry and biology of the bryostatin antitumour macrolides.

Review 5. A case study in biomimetic total synthesis: polyolefin carbocyclizations to terpenes and steroids.

6. Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina.

7. A stereoselective synthesis of (-)-tetrodotoxin.

Review 8. Biosynthesis of aromatic polyketides in bacteria.

Review 9. Function-oriented synthesis, step economy, and drug design.

Review 10. Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic sets.

1. Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis.

2. Rapid and stereochemically flexible synthesis of polypropionates: super-silyl-governed aldol cascades.

3. Strategies for recognition of stem-loop RNA structures by synthetic ligands: application to the HIV-1 frameshift stimulatory sequence.

4. Concise total synthesis of sintokamides A, B, and E by a unified, protecting-group-free strategy.

5. Evolution of an Efficient and Scalable Nine-Step (Longest Linear Sequence) Synthesis of Zincophorin Methyl Ester.

6. Merging allylic carbon-hydrogen and selective carbon-carbon bond activation.

7. Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis.

8. A robustness screen for the rapid assessment of chemical reactions.

9. Forming all-carbon quaternary stereogenic centres in acyclic systems from alkynes.

10. Fusarisetin A: Scalable Total Synthesis and Related Studies.