Literature DB >> 23956471

Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis.

Paul A Wender1.   

Abstract

Entities:  

Year:  2013        PMID： 23956471      PMCID： PMC3743450          DOI： 10.1016/j.tet.2013.06.004

Source DB:  PubMed          Journal:  Tetrahedron        ISSN： 0040-4020            Impact factor:   2.457


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  159 in total

1.  Introduction: Frontiers in Organic Synthesis.

Authors:  Paul A. Wender
Journal:  Chem Rev       Date:  1996-02-01       Impact factor: 60.622

2.  Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes.

Authors:  P A Wender; L Zhang
Journal:  Org Lett       Date:  2000-07-27       Impact factor: 6.005

3.  A molecular method for the delivery of small molecules and proteins across the cell wall of algae using molecular transporters.

Authors:  Joel M Hyman; Erika I Geihe; Brian M Trantow; Bahram Parvin; Paul A Wender
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-30       Impact factor: 11.205

4.  Enantioselective total synthesis of (-)-zampanolide, a potent microtubule-stabilizing agent.

Authors:  Arun K Ghosh; Xu Cheng
Journal:  Org Lett       Date:  2011-07-12       Impact factor: 6.005

5.  Tumor imaging by means of proteolytic activation of cell-penetrating peptides.

Authors:  Tao Jiang; Emilia S Olson; Quyen T Nguyen; Melinda Roy; Patricia A Jennings; Roger Y Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-15       Impact factor: 11.205

6.  Total synthesis of (-)-pseudolaric acid B.

Authors:  Barry M Trost; Jerome Waser; Arndt Meyer
Journal:  J Am Chem Soc       Date:  2007-11-07       Impact factor: 15.419

Review 7.  Function-oriented synthesis, step economy, and drug design.

Authors:  Paul A Wender; Vishal A Verma; Thomas J Paxton; Thomas H Pillow
Journal:  Acc Chem Res       Date:  2007-12-27       Impact factor: 22.384

8.  Enantioselective synthesis of 5,7-bicyclic ring systems from axially chiral allenes using a Rh(I)-catalyzed cyclocarbonylation reaction.

Authors:  Francois Grillet; Kay M Brummond
Journal:  J Org Chem       Date:  2013-03-29       Impact factor: 4.354

9.  Total synthesis and structural revision of the marine macrolide neopeltolide.

Authors:  Daniel W Custar; Thomas P Zabawa; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2008-01-23       Impact factor: 15.419

10.  A computationally designed Rh(I)-catalyzed two-component [5+2+1] cycloaddition of ene-vinylcyclopropanes and CO for the synthesis of cyclooctenones.

Authors:  Yuanyuan Wang; Jingxin Wang; Jiachun Su; Feng Huang; Lei Jiao; Yong Liang; Dazhi Yang; Shiwei Zhang; Paul A Wender; Zhi-Xiang Yu
Journal:  J Am Chem Soc       Date:  2007-07-27       Impact factor: 15.419
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  10 in total

1.  Bridging the gap between natural product synthesis and drug discovery.

Authors:  Nathanyal J Truax; Daniel Romo
Journal:  Nat Prod Rep       Date:  2020-10-26       Impact factor: 13.423

2.  Catalytic Efficiency Is a Function of How Rhodium(I) (5 + 2) Catalysts Accommodate a Conserved Substrate Transition State Geometry: Induced Fit Model for Explaining Transition Metal Catalysis.

Authors:  Thomas J L Mustard; Paul A Wender; Paul Ha-Yeon Cheong
Journal:  ACS Catal       Date:  2015-03-06       Impact factor: 13.084

3.  Synthesis of Tertiary Amines through Extrusive Alkylation of Carbamates.

Authors:  Guoliang Zhang; David Favela; Winston L Chow; Rishab N Iyer; Alexander J Pell; David E Olson
Journal:  Org Lett       Date:  2022-08-16       Impact factor: 6.072

4.  Late-Stage Diversification: A Motivating Force in Organic Synthesis.

Authors:  Kelly E Kim; Alexia N Kim; Carter J McCormick; Brian M Stoltz
Journal:  J Am Chem Soc       Date:  2021-10-06       Impact factor: 16.383

5.  Enantioselective synthesis of cyclopenta[b]benzofurans via an organocatalytic intramolecular double cyclization.

Authors:  Bruno Matos Paz; Yang Li; Mathias Kirk Thøgersen; Karl Anker Jørgensen
Journal:  Chem Sci       Date:  2017-10-02       Impact factor: 9.825

Review 6.  Limonoids From the Genus Melia (Meliaceae): Phytochemistry, Synthesis, Bioactivities, Pharmacokinetics, and Toxicology.

Authors:  Wenxiang Fan; Linhong Fan; Zhengtao Wang; Li Yang
Journal:  Front Pharmacol       Date:  2022-01-24       Impact factor: 5.810

7.  Mechanistic Insights on the Selectivity of the Tandem Heck-Ring-Opening of Cyclopropyldiol Derivatives.

Authors:  Anthony Cohen; Alexander Kaushansky; Ilan Marek
Journal:  JACS Au       Date:  2022-03-05

Review 8.  Recent developments in one-pot stepwise synthesis (OPSS) of small molecules.

Authors:  Xiaoming Ma; Wei Zhang
Journal:  iScience       Date:  2022-08-27

Review 9.  Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis.

Authors:  Erika A Crane; Karl Gademann
Journal:  Angew Chem Int Ed Engl       Date:  2016-02-02       Impact factor: 15.336

10.  Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp(3))-H arylation.

Authors:  Yunyun Liu; Yi Zhang; Xiaoji Cao; Jie-Ping Wan
Journal:  Beilstein J Org Chem       Date:  2016-06-03       Impact factor: 2.883
  10 in total

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