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Literature DB >> 19583255

Sortase-catalyzed peptide-glycosylphosphatidylinositol analogue ligation.

Xueqing Guo¹, Qianli Wang, Benjamin M Swarts, Zhongwu Guo.

Abstract

It is demonstrated that sortase A (SrtA) can catalyze efficient coupling of peptides to GPI analogues with a glycine residue attached to the phosphoethanolamine moiety at the nonreducing end to form GPI-linked peptides. This represents the first chemoenzymatic synthesis of GPI-peptide conjugates and is a proof-of-concept for the potential application of SrtA to the synthesis of more complex GPI-anchored peptides/glycopeptides and GPI-anchored proteins/glycoproteins.

Entities: Chemical Disease Gene

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Year: 2009 PMID： 19583255 DOI： 10.1021/ja903231v

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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Cited

25 in total

1. A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules.

Authors: James W Nelson; Alexander G Chamessian; Patrick J McEnaney; Ryan P Murelli; Barbara I Kazmierczak; Barbara I Kazmiercak; David A Spiegel
Journal: ACS Chem Biol Date: 2010-10-05 Impact factor: 5.100

Review 2. Enzymatic labeling of proteins: techniques and approaches.

Authors: Mohammad Rashidian; Jonathan K Dozier; Mark D Distefano
Journal: Bioconjug Chem Date: 2013-08-21 Impact factor: 4.774

3. Synthetic Studies of Glycosylphosphatidylinositol (GPI) Anchors and GPI-Anchored Peptides, Glycopeptides, and Proteins.

Authors: Zhongwu Guo
Journal: Curr Org Synth Date: 2013-06-01 Impact factor: 1.975

9. Isopeptide ligation catalyzed by quintessential sortase A: mechanistic cues from cyclic and branched oligomers of indolicidin.

Authors: Sayani Dasgupta; Sharmishtha Samantaray; Dinkar Sahal; Rajendra P Roy
Journal: J Biol Chem Date: 2011-05-12 Impact factor: 5.157

Review 10. Chemoenzymatic Methods for the Synthesis of Glycoproteins.

Authors: Chao Li; Lai-Xi Wang
Journal: Chem Rev Date: 2018-08-24 Impact factor: 60.622

Sortase-catalyzed peptide-glycosylphosphatidylinositol analogue ligation.

1. A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules.

Review 2. Enzymatic labeling of proteins: techniques and approaches.

3. Synthetic Studies of Glycosylphosphatidylinositol (GPI) Anchors and GPI-Anchored Peptides, Glycopeptides, and Proteins.

Review 4. Recent progress in synthetic and biological studies of GPI anchors and GPI-anchored proteins.

Review 5. Oligosaccharide Synthesis and Translational Innovation.

6. Sortase A-catalyzed peptide cyclization for the synthesis of macrocyclic peptides and glycopeptides.

Review 7. Chemical synthesis of glycosylphosphatidylinositol anchors.

8. New method for site-specific modification of liposomes with proteins using sortase A-mediated transpeptidation.

9. Isopeptide ligation catalyzed by quintessential sortase A: mechanistic cues from cyclic and branched oligomers of indolicidin.

Review 10. Chemoenzymatic Methods for the Synthesis of Glycoproteins.