Literature DB >> 19571755

Renal cancer surgery in the elderly.

Frederik C Roos1, Christian Hampel, Joachim W Thüroff.   

Abstract

PURPOSE OF REVIEW: Renal cell carcinoma mainly develops in the sixth or seventh decade of life. As life expectancy increases, urologists have to deal with elderly patients presenting with renal cancer. The introduction of ablative techniques has even widened our armamentarium of treating elderly patients with renal cancer apart from the standard laparoscopic and open surgical procedures. Our review highlights the current literature focusing on the functional and oncological outcome of surgically treated renal cancer in elderly patients. RECENT
FINDINGS: Despite the higher percentage of comorbidities, perioperative morbidity and declined renal reserve in elderly patients, radical or partial nephrectomy being performed open or laparoscopically for localized disease offers excellent functional and oncological outcome in this age group. Elderly patients seem to benefit more from laparoscopic procedures with lower rates of perioperative morbidity and faster convalescence compared with the open approach. Ablative techniques performed percutanousely may be promising for small renal masses in the future.
SUMMARY: Surgical treatment of renal cancer performed laparoscopically or open is feasible and well tolerated in elderly patients, with low perioperative morbidity and a good overall survival rate. Long-term results for ablative techniques are still missing for this age group. Patients should be carefully selected for one of the surgical treatments according to their health, fitness, wishes and the experience of the referred centre.

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Year:  2009        PMID: 19571755     DOI: 10.1097/MOU.0b013e32832f0c7d

Source DB:  PubMed          Journal:  Curr Opin Urol        ISSN: 0963-0643            Impact factor:   2.309


  7 in total

1.  Kidney cancer: treatment of clinically localized renal tumors in the elderly.

Authors:  Frederik C Roos; Joachim W Thüroff
Journal:  Nat Rev Urol       Date:  2011-10-11       Impact factor: 14.432

Review 2.  [Renal function in the elderly after radical tumor nephrectomy and partial nephrectomy].

Authors:  S Mehralivand; C Thomas; C Hampel; J W Thüroff; F C Roos
Journal:  Urologe A       Date:  2012-10       Impact factor: 0.639

3.  [Open and minimally invasive partial nephrectomy. Management of complications].

Authors:  C Wülfing; U Humke
Journal:  Urologe A       Date:  2014-07       Impact factor: 0.639

Review 4.  Renal Cancer in the Elderly.

Authors:  Tania González León; Maricela Morera Pérez
Journal:  Curr Urol Rep       Date:  2016-01       Impact factor: 3.092

5.  Interleukin-22 suppresses the growth of A498 renal cell carcinoma cells via regulation of STAT1 pathway.

Authors:  Fengbo Zhang; Donghao Shang; Yuhai Zhang; Ye Tian
Journal:  PLoS One       Date:  2011-05-23       Impact factor: 3.240

6.  The type of nephrectomy has little effect on overall survival or cardiac events in patients of 70 years and older with localized clinical t1 stage renal masses.

Authors:  Yoon Soo Kyung; Dalsan You; Taekmin Kwon; Sang Hoon Song; In Gab Jeong; Cheryn Song; Bumsik Hong; Jun Hyuk Hong; Hanjong Ahn; Choung-Soo Kim
Journal:  Korean J Urol       Date:  2014-07-11

7.  Renal surgery for kidney cancer in Germany 2005-2006: length of stay, risk of postoperative complications and in-hospital death.

Authors:  Andreas Stang; Christian Büchel
Journal:  BMC Urol       Date:  2014-09-12       Impact factor: 2.264

  7 in total

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