Literature DB >> 19571359

The physics behind the larger scale organization of DNA in eukaryotes.

Marc Emanuel1, Nima Hamedani Radja, Andreas Henriksson, Helmut Schiessel.   

Abstract

In this paper, we discuss in detail the organization of chromatin during a cell cycle at several levels. We show that current experimental data on large-scale chromatin organization have not yet reached the level of precision to allow for detailed modeling. We speculate in some detail about the possible physics underlying the larger scale chromatin organization.

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Year:  2009        PMID: 19571359     DOI: 10.1088/1478-3975/6/2/025008

Source DB:  PubMed          Journal:  Phys Biol        ISSN: 1478-3967            Impact factor:   2.583


  25 in total

1.  The fractal globule as a model of chromatin architecture in the cell.

Authors:  Leonid A Mirny
Journal:  Chromosome Res       Date:  2011-01       Impact factor: 5.239

2.  Structure-driven homology pairing of chromatin fibers: the role of electrostatics and protein-induced bridging.

Authors:  A G Cherstvy; V B Teif
Journal:  J Biol Phys       Date:  2013-01-17       Impact factor: 1.365

Review 3.  Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data.

Authors:  Job Dekker; Marc A Marti-Renom; Leonid A Mirny
Journal:  Nat Rev Genet       Date:  2013-05-09       Impact factor: 53.242

4.  A model for segregation of chromatin after replication: segregation of identical flexible chains in solution.

Authors:  Ron Dockhorn; Jens-Uwe Sommer
Journal:  Biophys J       Date:  2011-06-08       Impact factor: 4.033

Review 5.  Higher-order chromatin structure: bridging physics and biology.

Authors:  Geoffrey Fudenberg; Leonid A Mirny
Journal:  Curr Opin Genet Dev       Date:  2012-02-22       Impact factor: 5.578

Review 6.  Towards building a chromosome segregation machine.

Authors:  Kerry Bloom; Ajit Joglekar
Journal:  Nature       Date:  2010-01-28       Impact factor: 49.962

Review 7.  Revisiting higher-order and large-scale chromatin organization.

Authors:  Qian Bian; Andrew S Belmont
Journal:  Curr Opin Cell Biol       Date:  2012-03-27       Impact factor: 8.382

8.  Salt-modulated structure of polyelectrolyte-macroion complex fibers.

Authors:  Hoda Boroudjerdi; Ali Naji; Roland R Netz
Journal:  Eur Phys J E Soft Matter       Date:  2011-07-28       Impact factor: 1.890

9.  Inferential modeling of 3D chromatin structure.

Authors:  Siyu Wang; Jinbo Xu; Jianyang Zeng
Journal:  Nucleic Acids Res       Date:  2015-02-17       Impact factor: 16.971

10.  Toward a unified physical model of nucleosome patterns flanking transcription start sites.

Authors:  Wolfram Möbius; Brendan Osberg; Alexander M Tsankov; Oliver J Rando; Ulrich Gerland
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-18       Impact factor: 11.205

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