| Literature DB >> 19568884 |
Abstract
Mesothelioma is an aggressive tumor arising from the mesothelium, and is usually associated with previous exposure to asbestos. The incubation period of the tumor may be described as 30-40 years, and the prognosis is dismal. We previously discovered the Erc (Expressed in renal carcinoma) gene in the Eker rat model (Tsc2 gene mutant) and it was a homolog of the human mesothelin/MPF gene. We developed a novel ELISA system (N-ERC/mesothelin). Recently, we found that N-ERC/mesothelin was a potentially useful diagnostic marker for asbestos-related mesothelioma.Entities:
Year: 2008 PMID: 19568884 PMCID: PMC2698268 DOI: 10.1007/s12199-007-0014-9
Source DB: PubMed Journal: Environ Health Prev Med ISSN: 1342-078X Impact factor: 3.674