| Literature DB >> 19568264 |
Abstract
In the Notch pathway, the transmembrane ligand Delta is internalized and then re-established on the surface of signal-sending cells to allow the productive binding and activation of the Notch receptor on neighbouring cells. Arp2/3-dependent actin polymerization directs Delta trafficking through this circuit.Entities:
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Year: 2009 PMID: 19568264 DOI: 10.1038/ncb0709-791
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824