Literature DB >> 19564483

Recombinase-mediated cassette exchange provides a versatile platform for gene targeting: knockout of miR-31b.

Ruifen Weng1, Ya-Wen Chen, Natascha Bushati, Adam Cliffe, Stephen M Cohen.   

Abstract

A series of vectors has been designed to enhance the versatility of targeted homologous recombination. Recombinase-mediated cassette exchange permits sequential targeting at any locus and improves flexibility in making user-defined mutations. Application of RMCE to delete an intronic microRNA gene is described.

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Year:  2009        PMID: 19564483      PMCID: PMC2746163          DOI: 10.1534/genetics.109.105213

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  12 in total

1.  Gene targeting by homologous recombination in Drosophila.

Authors:  Y S Rong; K G Golic
Journal:  Science       Date:  2000-06-16       Impact factor: 47.728

2.  Ends-out, or replacement, gene targeting in Drosophila.

Authors:  Wei J Gong; Kent G Golic
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-14       Impact factor: 11.205

3.  Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour.

Authors:  Devanand S Manoli; Margit Foss; Adriana Villella; Barbara J Taylor; Jeffrey C Hall; Bruce S Baker
Journal:  Nature       Date:  2005-06-15       Impact factor: 49.962

4.  Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange.

Authors:  Jack R Bateman; Anne M Lee; C-ting Wu
Journal:  Genetics       Date:  2006-03-17       Impact factor: 4.562

5.  From the Cover: Directed, efficient, and versatile modifications of the Drosophila genome by genomic engineering.

Authors:  Juan Huang; Wenke Zhou; Wei Dong; Annie M Watson; Yang Hong
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-08       Impact factor: 11.205

6.  A targeted gene knockout in Drosophila.

Authors:  Y S Rong; K G Golic
Journal:  Genetics       Date:  2001-03       Impact factor: 4.562

7.  The white gene as a marker in a new P-element vector for gene transfer in Drosophila.

Authors:  R Klemenz; U Weber; W J Gehring
Journal:  Nucleic Acids Res       Date:  1987-05-26       Impact factor: 16.971

8.  Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.

Authors:  Walton D Jones; Pelin Cayirlioglu; Ilona Grunwald Kadow; Leslie B Vosshall
Journal:  Nature       Date:  2006-12-13       Impact factor: 49.962

9.  An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases.

Authors:  Johannes Bischof; Robert K Maeda; Monika Hediger; François Karch; Konrad Basler
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-22       Impact factor: 11.205

10.  The homologous chromosome is an effective template for the repair of mitotic DNA double-strand breaks in Drosophila.

Authors:  Yikang S Rong; Kent G Golic
Journal:  Genetics       Date:  2003-12       Impact factor: 4.562

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  24 in total

1.  A neuroprotective role for microRNA miR-1000 mediated by limiting glutamate excitotoxicity.

Authors:  Pushpa Verma; George J Augustine; Mohamed-Raafet Ammar; Ayumu Tashiro; Stephen M Cohen
Journal:  Nat Neurosci       Date:  2015-02-02       Impact factor: 24.884

2.  Use of microRNA sponges to explore tissue-specific microRNA functions in vivo.

Authors:  Stephen M Cohen
Journal:  Nat Methods       Date:  2009-12       Impact factor: 28.547

3.  Successive and targeted DNA integrations in the Drosophila genome by Bxb1 and phiC31 integrases.

Authors:  Juan Huang; Pallavi Ghosh; Graham F Hatfull; Yang Hong
Journal:  Genetics       Date:  2011-06-06       Impact factor: 4.562

Review 4.  Exploiting Drosophila genetics to understand microRNA function and regulation.

Authors:  Qi Dai; Peter Smibert; Eric C Lai
Journal:  Curr Top Dev Biol       Date:  2012       Impact factor: 4.897

5.  Long-range targeted manipulation of the Drosophila genome by site-specific integration and recombinational resolution.

Authors:  Natalia Wesolowska; Yikang S Rong
Journal:  Genetics       Date:  2012-11-12       Impact factor: 4.562

6.  Regulation of pattern formation and gene amplification during Drosophila oogenesis by the miR-318 microRNA.

Authors:  Wanzhong Ge; Qiannan Deng; Ting Guo; Xin Hong; Jan-Michael Kugler; Xiaohang Yang; Stephen M Cohen
Journal:  Genetics       Date:  2015-03-17       Impact factor: 4.562

7.  New research resources at the Bloomington Drosophila Stock Center.

Authors:  Kevin R Cook; Annette L Parks; Luke M Jacobus; Thomas C Kaufman; Kathleen A Matthews
Journal:  Fly (Austin)       Date:  2010-01-15       Impact factor: 2.160

8.  Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis.

Authors:  Valérie Hilgers; Natascha Bushati; Stephen M Cohen
Journal:  PLoS Biol       Date:  2010-06-15       Impact factor: 8.029

9.  Captured segment exchange: a strategy for custom engineering large genomic regions in Drosophila melanogaster.

Authors:  Jack R Bateman; Michael F Palopoli; Sarah T Dale; Jennifer E Stauffer; Anita L Shah; Justine E Johnson; Conor W Walsh; Hanna Flaten; Christine M Parsons
Journal:  Genetics       Date:  2012-11-12       Impact factor: 4.562

Review 10.  Genome engineering: Drosophila melanogaster and beyond.

Authors:  Koen J T Venken; Alejandro Sarrion-Perdigones; Paul J Vandeventer; Nicholas S Abel; Audrey E Christiansen; Kristi L Hoffman
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2015-10-08       Impact factor: 5.814

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