| Literature DB >> 19564483 |
Ruifen Weng1, Ya-Wen Chen, Natascha Bushati, Adam Cliffe, Stephen M Cohen.
Abstract
A series of vectors has been designed to enhance the versatility of targeted homologous recombination. Recombinase-mediated cassette exchange permits sequential targeting at any locus and improves flexibility in making user-defined mutations. Application of RMCE to delete an intronic microRNA gene is described.Mesh:
Substances:
Year: 2009 PMID: 19564483 PMCID: PMC2746163 DOI: 10.1534/genetics.109.105213
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562