Literature DB >> 19551732

Acylated oleanane-type triterpene saponins with acceleration of gastrointestinal transit and inhibitory effect on pancreatic lipase from flower buds of chinese tea plant (Camellia sinensis).

Masayuki Yoshikawa1, Sachiko Sugimoto, Yasuyo Kato, Seikou Nakamura, Tao Wang, Chihiro Yamashita, Hisashi Matsuda.   

Abstract

The MeOH extract and its BuOH-soluble fraction (crude saponin fraction) from the flower buds of Chinese tea plant (Camellia sinensis (L.) O. KUNTZE; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice and inhibitory effects against pancreatic lipase. From the BuOH-soluble fraction, three new acylated oleanane-type triterpene oligoglycosides, chakasaponins I, II, and III (1-3, resp.), were isolated together with 13 known compounds. The chemical structures 1-3 were elucidated on the basis of chemical and physicochemical evidence. Compounds 1-3 showed accelerating effects on gastrointestinal transit in mice and inhibitory effects against porcine pancreatic lipase (IC(50)=150-530 microM).

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Year:  2009        PMID： 19551732     DOI： 10.1002/cbdv.200800153

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  10 in total

1.  Quantitative analysis of acylated oleanane-type triterpene saponins, chakasaponins I-III and floratheasaponins A-F, in the flower buds of Camellia sinensis from different regional origins.

Authors:  Toshio Morikawa; Sohachiro Miyake; Yoshinobu Miki; Kiyofumi Ninomiya; Masayuki Yoshikawa; Osamu Muraoka
Journal:  J Nat Med       Date:  2012-02-04       Impact factor: 2.343

2.  Anti-proliferative effect and cell cycle arrest induced by saponins extracted from tea (Camellia sinensis) flower in human ovarian cancer cells.

Authors:  Yaomin Wang; Ning Ren; Gary O Rankin; Bo Li; Yon Rojanasakul; Youying Tu; Yi Charlie Chen
Journal:  J Funct Foods       Date:  2017-08-10       Impact factor: 4.451

3.  The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents.

Authors:  Sonia A Tucci; Emma J Boyland; Jason Cg Halford
Journal:  Diabetes Metab Syndr Obes       Date:  2010-05-10       Impact factor: 3.168

4.  Purified Tea (Camellia sinensis (L.) Kuntze) Flower Saponins Induce the p53-Dependent Intrinsic Apoptosis of Cisplatin-Resistant Ovarian Cancer Cells.

Authors:  Ning Ren; Lianfu Chen; Bo Li; Gary O Rankin; Yi Charlie Chen; Youying Tu
Journal:  Int J Mol Sci       Date:  2020-06-17       Impact factor: 5.923

Review 5.  Occurrence of Functional Molecules in the Flowers of Tea (Camellia sinensis) Plants: Evidence for a Second Resource.

Authors:  Yiyong Chen; Ying Zhou; Lanting Zeng; Fang Dong; Youying Tu; Ziyin Yang
Journal:  Molecules       Date:  2018-03-29       Impact factor: 4.411

Review 6.  A Comprehensive Insight on the Health Benefits and Phytoconstituents of Camellia sinensis and Recent Approaches for Its Quality Control.

Authors:  Maram M Aboulwafa; Fadia S Youssef; Haidy A Gad; Ahmed E Altyar; Mohamed M Al-Azizi; Mohamed L Ashour
Journal:  Antioxidants (Basel)       Date:  2019-10-06

7.  Purification of Tea Saponins and Evaluation of its Effect on Alcohol Dehydrogenase Activity.

Authors:  Chuanxun Yuan; Yan Li; Qingchuan Li; Risheng Jin; Lili Ren
Journal:  Open Life Sci       Date:  2018-04-10       Impact factor: 0.938

Review 8.  Inhibitors of pancreatic lipase: state of the art and clinical perspectives.

Authors:  Nitin A Lunagariya; Neeraj K Patel; Sneha C Jagtap; Kamlesh K Bhutani
Journal:  EXCLI J       Date:  2014-08-22       Impact factor: 4.068

Review 9.  New biofunctional effects of the flower buds of Camellia sinensis and its bioactive acylated oleanane-type triterpene oligoglycosides.

Authors:  Hisashi Matsuda; Seikou Nakamura; Toshio Morikawa; Osamu Muraoka; Masayuki Yoshikawa
Journal:  J Nat Med       Date:  2016-07-05       Impact factor: 2.343

10.  Tea silkworm droppings as an enriched source of tea flavonoids.

Authors:  Tzu-Yun Chou; Meei-Ju Yang; Shih-Kung Tseng; Shoei-Sheng Lee; Chia-Chuan Chang
Journal:  J Food Drug Anal       Date:  2017-01-25       Impact factor: 6.157
  10 in total

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