Literature DB >> 19549436

Payment of egg donors in stem cell research in the USA.

Robert Klitzman1, Mark V Sauer.   

Abstract

Arguments have been put forth as to whether women who donate oocytes for human embryonic stem cell (HESC) research should be compensated, but data regarding this issue have been scant. Recently in the United States, several States have begun funding HESC research, and patient recruitment efforts have begun. This paper lays out relevant arguments and presents data concerning this issue. Researchers are finding that women are unwilling to donate eggs altruistically, which is hampering the progress of research. These efforts are examined, and data on potential donors' views are presented. The absence of payment, rather than ethical concerns, appears to explain opposition to donation. Women also appear generally ignorant of policies in this area. It is suggested that policy discussions shift focus from whether to pay, to how much would be appropriate, and how to decide; and that research and public and professional education be increased to heighten understanding and awareness of these issues.

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Mesh:

Year:  2009        PMID: 19549436      PMCID: PMC3667654          DOI: 10.1016/s1472-6483(10)60002-8

Source DB:  PubMed          Journal:  Reprod Biomed Online        ISSN: 1472-6483            Impact factor:   3.828


  25 in total

1.  Financial incentives in recruitment of oocyte donors. The Ethics Committee of the American Society for Reproductive Medicine.

Authors: 
Journal:  Fertil Steril       Date:  2000-08       Impact factor: 7.329

Review 2.  Ending concerns about undue inducement.

Authors:  Ezekiel J Emanuel
Journal:  J Law Med Ethics       Date:  2004       Impact factor: 1.718

3.  Reproductive tourism and the regulatory map.

Authors:  Debora Spar
Journal:  N Engl J Med       Date:  2005-02-10       Impact factor: 91.245

4.  Stem cells. Ethical oocytes: available for a price.

Authors:  Gretchen Vogel
Journal:  Science       Date:  2006-07-14       Impact factor: 47.728

5.  Ethics. The ISSCR guidelines for human embryonic stem cell research.

Authors:  George Q Daley; Lars Ahrlund Richter; Jonathan M Auerbach; Nissim Benvenisty; R Alta Charo; Grace Chen; Hong-Kui Deng; Lawrence S Goldstein; Kathy L Hudson; Insoo Hyun; Sung Chull Junn; Jane Love; Eng Hin Lee; Anne McLaren; Christine L Mummery; Norio Nakatsuji; Catherine Racowsky; Heather Rooke; Janet Rossant; Hans R Schöler; Jan Helge Solbakk; Patrick Taylor; Alan O Trounson; Irving L Weissman; Ian Wilmut; John Yu; Laurie Zoloth
Journal:  Science       Date:  2007-02-02       Impact factor: 47.728

6.  The egg trade--making sense of the market for human oocytes.

Authors:  Debora Spar
Journal:  N Engl J Med       Date:  2007-03-29       Impact factor: 91.245

7.  Views of the process and content of ethical reviews of HIV vaccine trials among members of US institutional review boards and South African research ethics committees.

Authors:  Robert Klitzman
Journal:  Dev World Bioeth       Date:  2008-12       Impact factor: 2.294

Review 8.  Fertility drugs and gynecologic cancer.

Authors:  Nikos Kanakas; Themis Mantzavinos
Journal:  Ann N Y Acad Sci       Date:  2006-12       Impact factor: 5.691

9.  Donating eggs for research--should the HFEA reconsider its policy on payments to egg donors?

Authors:  Joanne Ramsey
Journal:  Reprod Biomed Online       Date:  2007-09       Impact factor: 3.828

10.  A Review of Paying Research Participants: It's Time to Move Beyond the ethical Debate.

Authors:  Elizabeth B D Ripley
Journal:  J Empir Res Hum Res Ethics       Date:  2006-12       Impact factor: 1.742

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  6 in total

1.  Stem cell research, scientific freedom and the commodification concern.

Authors:  Timothy Caulfield; Ubaka Ogbogu
Journal:  EMBO Rep       Date:  2011-12-23       Impact factor: 8.807

2.  Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes.

Authors:  L Zakarin Safier; A Gumer; M Kline; D Egli; M V Sauer
Journal:  J Assist Reprod Genet       Date:  2018-06-05       Impact factor: 3.412

3.  Human oocytes reprogram somatic cells to a pluripotent state.

Authors:  Scott Noggle; Ho-Lim Fung; Athurva Gore; Hector Martinez; Kathleen Crumm Satriani; Robert Prosser; Kiboong Oum; Daniel Paull; Sarah Druckenmiller; Matthew Freeby; Ellen Greenberg; Kun Zhang; Robin Goland; Mark V Sauer; Rudolph L Leibel; Dieter Egli
Journal:  Nature       Date:  2011-10-05       Impact factor: 49.962

4.  Research ethics. NIH guidelines for stem cell research and gamete donors.

Authors:  Bernard Lo; Lindsay Parham; Marcelle Cedars; Susan Fisher; Elena Gates; Linda Giudice; Dina Gould Halme; William Hershon; Arnold Kriegstein; Radhika Rao; Clifford Roberts; Richard Wagner
Journal:  Science       Date:  2010-02-19       Impact factor: 47.728

5.  Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells.

Authors:  Mitsutoshi Yamada; Bjarki Johannesson; Ido Sagi; Lisa Cole Burnett; Daniel H Kort; Robert W Prosser; Daniel Paull; Michael W Nestor; Matthew Freeby; Ellen Greenberg; Robin S Goland; Rudolph L Leibel; Susan L Solomon; Nissim Benvenisty; Mark V Sauer; Dieter Egli
Journal:  Nature       Date:  2014-04-28       Impact factor: 49.962

6.  Juggling on a rollercoaster? Gains, loss and uncertainties in IVF patients' accounts of volunteering for a U.K. 'egg sharing for research' scheme.

Authors:  Erica Haimes
Journal:  Soc Sci Med       Date:  2013-03-13       Impact factor: 4.634

  6 in total

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