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Literature DB >> 19546856

Fitness and its role in evolutionary genetics.

Abstract

Although the operation of natural selection requires that genotypes differ in fitness, some geneticists may find it easier to understand natural selection than fitness. Partly this reflects the fact that the word 'fitness' has been used to mean subtly different things. In this Review I distinguish among these meanings (for example, individual fitness, absolute fitness and relative fitness) and explain how evolutionary geneticists use fitness to predict changes in the genetic composition of populations through time. I also review the empirical study of fitness, emphasizing approaches that take advantage of recent genetic and genomic data, and I highlight important unresolved problems in understanding fitness.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2009 PMID： 19546856 PMCID： PMC2753274 DOI： 10.1038/nrg2603

Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242

51 in total

1. Perspective: Here's to Fisher, additive genetic variance, and the fundamental theorem of natural selection.

Authors: James F Crow
Journal: Evolution Date: 2002-07 Impact factor: 3.694

2. A review of some fundamental concepts and problems of population genetics.

Authors: T DOBZHANSKY
Journal: Cold Spring Harb Symp Quant Biol Date: 1955

3. Absolute fitness, relative fitness, and utility.

Authors: H Allen Orr
Journal: Evolution Date: 2007-10-30 Impact factor: 3.694

Review 4. The locus of evolution: evo devo and the genetics of adaptation.

Authors: Hopi E Hoekstra; Jerry A Coyne
Journal: Evolution Date: 2007-05 Impact factor: 3.694

5. Alternative fitness models with the same allele frequency dynamics.

Authors: C Denniston; J F Crow
Journal: Genetics Date: 1990-05 Impact factor: 4.562

6. Evolution of high mutation rates in experimental populations of E. coli.

Authors: P D Sniegowski; P J Gerrish; R E Lenski
Journal: Nature Date: 1997-06-12 Impact factor: 49.962

7. Natural selection and the concept of a protein space.

Authors: J M Smith
Journal: Nature Date: 1970-02-07 Impact factor: 49.962

8. Selection and covariance.

Authors: G R Price
Journal: Nature Date: 1970-08-01 Impact factor: 49.962

9. Adaptive protein evolution in Drosophila.

Authors: Nick G C Smith; Adam Eyre-Walker
Journal: Nature Date: 2002-02-28 Impact factor: 49.962

10. Understanding the evolutionary fate of finite populations: the dynamics of mutational effects.

Authors: Olin K Silander; Olivier Tenaillon; Lin Chao
Journal: PLoS Biol Date: 2007-04 Impact factor: 8.029

146 in total

1. Competitive and cooperative metabolic interactions in bacterial communities.

Authors: Shiri Freilich; Raphy Zarecki; Omer Eilam; Ella Shtifman Segal; Christopher S Henry; Martin Kupiec; Uri Gophna; Roded Sharan; Eytan Ruppin
Journal: Nat Commun Date: 2011-12-13 Impact factor: 14.919

2. Limits of neutral drift: lessons from the in vitro evolution of two ribozymes.

Authors: Katherine L Petrie; Gerald F Joyce
Journal: J Mol Evol Date: 2014-08-26 Impact factor: 2.395

3. A high level of mutation tolerance in the multifunctional sequence encoding the RNA encapsidation signal of an avian hepatitis B virus and slow evolution rate revealed by in vivo infection.

Authors: Bernadette Schmid; Christine Rösler; Michael Nassal
Journal: J Virol Date: 2011-07-13 Impact factor: 5.103

Fitness and its role in evolutionary genetics.

1. Perspective: Here's to Fisher, additive genetic variance, and the fundamental theorem of natural selection.

2. A review of some fundamental concepts and problems of population genetics.

3. Absolute fitness, relative fitness, and utility.

Review 4. The locus of evolution: evo devo and the genetics of adaptation.

5. Alternative fitness models with the same allele frequency dynamics.

6. Evolution of high mutation rates in experimental populations of E. coli.

7. Natural selection and the concept of a protein space.

8. Selection and covariance.

9. Adaptive protein evolution in Drosophila.

10. Understanding the evolutionary fate of finite populations: the dynamics of mutational effects.

1. Competitive and cooperative metabolic interactions in bacterial communities.

2. Limits of neutral drift: lessons from the in vitro evolution of two ribozymes.

3. A high level of mutation tolerance in the multifunctional sequence encoding the RNA encapsidation signal of an avian hepatitis B virus and slow evolution rate revealed by in vivo infection.

4. Hamiltonian inclusive fitness: a fitter fitness concept.

5. Probing the basis for genotype-phenotype relationships.

6. A reinforcement learning mechanism responsible for the valuation of free choice.

7. Dispersal and selection mediate hybridization between a native and invasive species.

Review 8. Measuring intolerance to mutation in human genetics.

Review 9. Modeling Tumor Clonal Evolution for Drug Combinations Design.

10. Measuring the sensitivity of single-locus "neutrality tests" using a direct perturbation approach.