Maurice W Dysken1, Laura Nelson Kirk, Michael Kuskowski. 1. Geriatric Research, Education, and Clinical Center Program, Minneapolis VA Medical Center, Minneapolis, MN 55417, USA. maurice.dysken@med.va.gov
Abstract
OBJECTIVE: At the end of 2006, a survey was sent to members of the American Association of Geriatric Psychiatry (AAGP) to assess possible changes in prescribing Vitamin E to patients with Alzheimer disease that followed two published reports in early 2005 suggesting increased mortality and an increased incidence of heart failure with Vitamin E supplements. METHOD: A three-item questionnaire was mailed to all AAGP members who had prescription privileges to assess changes in prescribing Vitamin E after January, 2005. RESULTS: A total of 572 completed surveys were returned for a response rate of 35%. Nearly 60% of respondents reported a change over the 2 years that followed the 2005 reports. The greatest change was in the group not prescribing Vitamin E, which increased from 6.6% before 2005 to 60.6% afterward. CONCLUSIONS: AAGP members significantly reduced prescribing Vitamin E to patients with Alzheimer disease after 2005. The two reports are discussed with an emphasis on their methodological limitations and the potential for additional information on Vitamin E side effects from ongoing research.
OBJECTIVE: At the end of 2006, a survey was sent to members of the American Association of Geriatric Psychiatry (AAGP) to assess possible changes in prescribing Vitamin E to patients with Alzheimer disease that followed two published reports in early 2005 suggesting increased mortality and an increased incidence of heart failure with Vitamin E supplements. METHOD: A three-item questionnaire was mailed to all AAGP members who had prescription privileges to assess changes in prescribing Vitamin E after January, 2005. RESULTS: A total of 572 completed surveys were returned for a response rate of 35%. Nearly 60% of respondents reported a change over the 2 years that followed the 2005 reports. The greatest change was in the group not prescribing Vitamin E, which increased from 6.6% before 2005 to 60.6% afterward. CONCLUSIONS: AAGP members significantly reduced prescribing Vitamin E to patients with Alzheimer disease after 2005. The two reports are discussed with an emphasis on their methodological limitations and the potential for additional information on Vitamin E side effects from ongoing research.
Authors: Maurice W Dysken; Mary Sano; Sanjay Asthana; Julia E Vertrees; Muralidhar Pallaki; Maria Llorente; Susan Love; Gerard D Schellenberg; J Riley McCarten; Julie Malphurs; Susana Prieto; Peijun Chen; David J Loreck; George Trapp; Rajbir S Bakshi; Jacobo E Mintzer; Judith L Heidebrink; Ana Vidal-Cardona; Lillian M Arroyo; Angel R Cruz; Sally Zachariah; Neil W Kowall; Mohit P Chopra; Suzanne Craft; Stephen Thielke; Carolyn L Turvey; Catherine Woodman; Kimberly A Monnell; Kimberly Gordon; Julie Tomaska; Yoav Segal; Peter N Peduzzi; Peter D Guarino Journal: JAMA Date: 2014-01-01 Impact factor: 56.272
Authors: Maurice W Dysken; Peter D Guarino; Julia E Vertrees; Sanjay Asthana; Mary Sano; Maria Llorente; Muralidhar Pallaki; Susan Love; Gerard D Schellenberg; J Riley McCarten; Julie Malphurs; Susana Prieto; Peijun Chen; David J Loreck; Sara Carney; George Trapp; Rajbir S Bakshi; Jacobo E Mintzer; Judith L Heidebrink; Ana Vidal-Cardona; Lillian M Arroyo; Angel R Cruz; Neil W Kowall; Mohit P Chopra; Suzanne Craft; Stephen Thielke; Carolyn L Turvey; Catherine Woodman; Kimberly A Monnell; Kimberly Gordon; Julie Tomaska; Govind Vatassery Journal: Alzheimers Dement Date: 2013-04-11 Impact factor: 21.566
Authors: Nicolas Farina; Mokhtar Gad El Kareem Nasr Isaac; Annalie R Clark; Jennifer Rusted; Naji Tabet Journal: Cochrane Database Syst Rev Date: 2012-11-14
Authors: Francisco de Assis Carvalho do Vale; Ylmar Corrêa Neto; Paulo Henrique Ferreira Bertolucci; João Carlos Barbosa Machado; Delson José da Silva; Nasser Allam; Márcio Luiz Figueredo Balthazar Journal: Dement Neuropsychol Date: 2011 Jul-Sep