Literature DB >> 19544808

Characterization of a mini-multileaf collimator in a proton beamline.

J Daartz1, M Bangert, M R Bussière, M Engelsman, H M Kooy.   

Abstract

A mini-multileaf collimator (MMLC) was mounted as a field shaping collimator in a proton beamline at the Massachusetts General Hospital. The purpose is to evaluate the device's dosimetric and mechanical properties for the use in a proton beamline. For this evaluation, the authors compared MMLC and brass aperture shaped dose distributions with regard to lateral and depth dose properties. The lateral fall off is generally broader with the MMLC, with difference varying with proton range from 0.2 to 1.2 mm. Central axis depth dose curves did not show a difference in peak-to-entrance ratio, peak width, distal fall off, or range. Two-dimensional dose distributions to investigate the conformity of MMLC shaped doses show that the physical leaf width of approximately 2.5 mm does not have a significant impact. All differences seen in dose distribution shaped by the MMLC versus brass apertures were shown to be clinically insignificant. Measured neutron doses of 0.03-0.13 mSv/Gy for a closed brass beam block (depending on range) are very low compared to the previously published data. Irradiation of the tungsten MMLC, however, produced 1.5-1.8 times more neutrons than brass apertures. Exposure of the staff resulting from activation of the device is below regulatory limits. The measurements established an equivalency between aperture and MMLC shaped dose distributions.

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Year:  2009        PMID: 19544808     DOI: 10.1118/1.3116382

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  6 in total

1.  Trimmer sequencing time minimization during dynamically collimated proton therapy using a colony of cooperating agents.

Authors:  Blake R Smith; Daniel E Hyer; Ryan T Flynn; Patrick M Hill; Wesley S Culberson
Journal:  Phys Med Biol       Date:  2019-10-21       Impact factor: 3.609

2.  Mechanical Characterization and Validation of the Dynamic Collimation System Prototype for Proton Radiotherapy.

Authors:  Theodore Geoghegan; Kaustubh Patwardhan; Nicholas Nelson; Patrick Hill; Ryan Flynn; Blake Smith; Daniel Hyer
Journal:  J Med Device       Date:  2022-03-02       Impact factor: 0.743

3.  Design of a focused collimator for proton therapy spot scanning using Monte Carlo methods.

Authors:  Theodore J Geoghegan; Nicholas P Nelson; Ryan T Flynn; Patrick M Hill; Suresh Rana; Daniel E Hyer
Journal:  Med Phys       Date:  2020-04-06       Impact factor: 4.071

4.  Reducing the cost of proton radiation therapy: the feasibility of a streamlined treatment technique for prostate cancer.

Authors:  Wayne D Newhauser; Rui Zhang; Timothy G Jones; Annelise Giebeler; Phillip J Taddei; Robert D Stewart; Andrew Lee; Oleg Vassiliev
Journal:  Cancers (Basel)       Date:  2015-04-24       Impact factor: 6.639

5.  Proton therapy needs further technological development to fulfill the promise of becoming a superior treatment modality (compared to photon therapy).

Authors:  Daniel E Hyer; Xuanfeng Ding; Yi Rong
Journal:  J Appl Clin Med Phys       Date:  2021-11-03       Impact factor: 2.102

6.  Innovations and the Use of Collimators in the Delivery of Pencil Beam Scanning Proton Therapy.

Authors:  Daniel E Hyer; Laura C Bennett; Theodore J Geoghegan; Martin Bues; Blake R Smith
Journal:  Int J Part Ther       Date:  2021-06-25
  6 in total

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