Literature DB >> 19542311

Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms.

Koen W A van Grinsven1, Jan Van Den Abbeele, Peter Van den Bossche, Jaap J van Hellemond, Aloysius G M Tielens.   

Abstract

Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

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Year:  2009        PMID： 19542311      PMCID： PMC2725551          DOI： 10.1128/EC.00091-09

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN： 1535-9786


  26 in total

1.  Trypanosoma brucei spp. development in the tsetse fly: characterization of the post-mesocyclic stages in the foregut and proboscis.

Authors:  J Van Den Abbeele; Y Claes; D van Bockstaele; D Le Ray; M Coosemans
Journal:  Parasitology       Date:  1999-05       Impact factor: 3.234

2.  Mitochondrial development in Trypanosoma brucei brucei transitional bloodstream forms.

Authors:  E J Bienen; M Saric; G Pollakis; R W Grady; A B Clarkson
Journal:  Mol Biochem Parasitol       Date:  1991-04       Impact factor: 1.759

Review 3.  Complex I of Trypanosomatidae: does it exist?

Authors:  Fred R Opperdoes; Paul A M Michels
Journal:  Trends Parasitol       Date:  2008-06-03

4.  Differential mitochondrial gene expression between slender and stumpy bloodforms of Trypanosoma brucei.

Authors:  J E Feagin; D P Jasmer; K Stuart
Journal:  Mol Biochem Parasitol       Date:  1986-09       Impact factor: 1.759

5.  The metabolism of carbohydrate by pleomorphic African trypanosomes.

Authors:  I W Flynn; I B Bowman
Journal:  Comp Biochem Physiol B       Date:  1973-05-15

Review 6.  Energy generation in insect stages of Trypanosoma brucei: metabolism in flux.

Authors:  Sébastien Besteiro; Michael P Barrett; Loïc Rivière; Frédéric Bringaud
Journal:  Trends Parasitol       Date:  2005-04

7.  Trypanosomatidae produce acetate via a mitochondrial acetate:succinate CoA transferase.

Authors:  J J Van Hellemond; F R Opperdoes; A G Tielens
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-17       Impact factor: 11.205

Review 8.  The trypanosomiases.

Authors:  Michael P Barrett; Richard J S Burchmore; August Stich; Julio O Lazzari; Alberto Carlos Frasch; Juan José Cazzulo; Sanjeev Krishna
Journal:  Lancet       Date:  2003-11-01       Impact factor: 79.321

9.  Procyclic Trypanosoma brucei do not use Krebs cycle activity for energy generation.

Authors:  Susanne W H van Weelden; Beate Fast; Achim Vogt; Pieter van der Meer; Joachim Saas; Jaap J van Hellemond; Aloysius G M Tielens; Michael Boshart
Journal:  J Biol Chem       Date:  2003-01-31       Impact factor: 5.157

10.  Evolution of energy metabolism and its compartmentation in Kinetoplastida.

Authors:  Véronique Hannaert; Frédéric Bringaud; Fred R Opperdoes; Paul AM Michels
Journal:  Kinetoplastid Biol Dis       Date:  2003-10-28
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  15 in total

1.  ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.

Authors:  Ana Brennand; Eva Rico; Daniel J Rigden; Patrick Van Der Smissen; Pierre J Courtoy; Paul A M Michels
Journal:  PLoS One       Date:  2015-06-19       Impact factor: 3.240

2.  Overexpression of Plasmodium berghei ATG8 by Liver Forms Leads to Cumulative Defects in Organelle Dynamics and to Generation of Noninfectious Merozoites.

Authors:  Christiane Voss; Karen Ehrenman; Godfree Mlambo; Satish Mishra; Kota Arun Kumar; John B Sacci; Photini Sinnis; Isabelle Coppens
Journal:  MBio       Date:  2016-06-28       Impact factor: 7.867

Review 3.  A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex.

Authors:  Alena Zíková; Zdeněk Verner; Anna Nenarokova; Paul A M Michels; Julius Lukeš
Journal:  PLoS Pathog       Date:  2017-12-21       Impact factor: 6.823

4.  A FRET flow cytometry method for monitoring cytosolic and glycosomal glucose in living kinetoplastid parasites.

Authors:  Charles M Voyton; Yijian Qiu; Meredith T Morris; P Christine Ackroyd; Jimmy Suryadi; Logan Crowe; James C Morris; Kenneth A Christensen
Journal:  PLoS Negl Trop Dis       Date:  2018-05-31

5.  Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.

Authors:  Pieter C Steketee; Emily A Dickie; James Iremonger; Kathryn Crouch; Edith Paxton; Siddharth Jayaraman; Omar A Alfituri; Georgina Awuah-Mensah; Ryan Ritchie; Achim Schnaufer; Tim Rowan; Harry P de Koning; Catarina Gadelha; Bill Wickstead; Michael P Barrett; Liam J Morrison
Journal:  PLoS Pathog       Date:  2021-07-26       Impact factor: 6.823

6.  Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry.

Authors:  Kapila Gunasekera; Daniel Wüthrich; Sophie Braga-Lagache; Manfred Heller; Torsten Ochsenreiter
Journal:  BMC Genomics       Date:  2012-10-16       Impact factor: 3.969

7.  Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability.

Authors:  Muriel Mazet; Pauline Morand; Marc Biran; Guillaume Bouyssou; Pierrette Courtois; Sylvie Daulouède; Yoann Millerioux; Jean-Michel Franconi; Philippe Vincendeau; Patrick Moreau; Frédéric Bringaud
Journal:  PLoS Negl Trop Dis       Date:  2013-12-19

Review 8.  Metabolic reprogramming during the Trypanosoma brucei life cycle.

Authors:  Terry K Smith; Frédéric Bringaud; Derek P Nolan; Luisa M Figueiredo
Journal:  F1000Res       Date:  2017-05-16

Review 9.  The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids.

Authors:  Letícia Marchese; Janaina de Freitas Nascimento; Flávia Silva Damasceno; Frédéric Bringaud; Paul A M Michels; Ariel Mariano Silber
Journal:  Pathogens       Date:  2018-04-01

10.  Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.

Authors:  Caroline E Dewar; Paula MacGregor; Sinclair Cooper; Matthew K Gould; Keith R Matthews; Nicholas J Savill; Achim Schnaufer
Journal:  PLoS Pathog       Date:  2018-07-18       Impact factor: 6.823
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