Literature DB >> 19540823

Reconstruction of full thickness scalp defects after tumour excision in elderly patients: our experience with Integra dermal regeneration template.

B Corradino1, S Di Lorenzo, A A Leto Barone, E Maresi, F Moschella.   

Abstract

BACKGROUND: Scalp reconstruction after wide tumor excision is particularly challenging. Free tissue transfers, local flaps, or skin grafts can be used but present some disadvantages especially with old patients with local advanced cancers, systemic diseases and in patients with a prior history of recurring scalp skin cancers in which the risk of burying a recurring tumor with a flap is likely. The Authors expose their early experience with Integra dermal regeneration template for scalp reconstruction after scalp tumor excision.
METHODS: Eight patients with primary or secondary scalp tumor underwent a first surgical procedure under local anaesthesia for tumor removal and Integra positioning followed by a second operation performed three weeks later to reconstruct the defect by removing the superficial silicon layer of Integra and by covering the defect with a split thickness skin graft. The average surface area of the defect was 143.27 cm(2). The average operating time was 30.4 minutes for the first operation and 45.6 minutes for the second operation. In six cases Integra was grafted as a classic full-thickness skin graft. In the remaining two cases the Integra template was meshed. The artificial derma was attached to the edge of the wound by either sutures or staples.
RESULTS: There was a full graft take on all cases. The mean follow-up was 24 months. In two cases we were able to detect early tumor recurrence two months after the operation. Satisfactory cosmetic and functional results were obtained in all patients.
CONCLUSIONS: In the scalp defect reconstructions after tumor excision, Integra allows to obtain a thicker and more durable coverage than skin graft on the skull, allowing to detect a tumor recurrence earlier than a flap reconstruction with no risk of burying an eventual underlying residual tumor. These operations are performed under local anaesthesia and are therefore suitable for elderly patients. (c) 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

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Year:  2009        PMID: 19540823     DOI: 10.1016/j.bjps.2009.05.038

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  11 in total

1.  [Surgical wounds of the scalp. Methods of closure].

Authors:  M Meissner; R Kaufmann
Journal:  Hautarzt       Date:  2011-05       Impact factor: 0.751

2.  The role of full-thickness scalp resection for management of primary scalp melanoma.

Authors:  Christopher J Pannucci; Ryan M Collar; Timothy M Johnson; Carol R Bradford; Riley S Rees
Journal:  Ann Plast Surg       Date:  2012-08       Impact factor: 1.539

Review 3.  Infectious Complications Associated with the Use of Integra: A Systematic Review of the Literature.

Authors:  Santiago R Gonzalez; Keith G Wolter; James C Yuen
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-07-15

4.  Lessons Learned in Scalp Reconstruction and Tailoring Free Tissue Transfer in the Elderly: A Case Series and Literature Review.

Authors:  Michael Sosin; Arif Chaudhry; Carla De La Cruz; Branko Bojovic; Paul N Manson; Eduardo D Rodriguez
Journal:  Craniomaxillofac Trauma Reconstr       Date:  2014-11-24

Review 5.  Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2-stage surgical protocol for the treatment of non-melanoma skin cancers of the head in fragile patients.

Authors:  Marco Marcasciano; Marco Mazzocchi; Juste Kaciulyte; Noemi Spissu; Donato Casella; Diego Ribuffo; Luca Andrea Dessy
Journal:  Int Wound J       Date:  2018-06-04       Impact factor: 3.315

6.  Reconstruction following Excision of Malignant Scalp Tumors with Split Thickness Skin Graft with and without Acellular Dermal Matrix: A Comparative Study.

Authors:  Javad Rahmati; Soheil Boroumand; Koroush Ghanbarzadeh; Shahriar Haddady Abianeh; Hojjat Molaei; Afshin Fathi; Arjang Ghahremani; Omid Etemad
Journal:  J Cutan Aesthet Surg       Date:  2019 Oct-Dec

7.  Reconstruction of Extensive Calvarial Exposure After Major Burn Injury in 2 Stages Using a Biodegradable Polyurethane Matrix.

Authors:  John Edward Greenwood; Marcus James Dermot Wagstaff; Michael Rooke; Yugesh Caplash
Journal:  Eplasty       Date:  2016-05-09

8.  One-Stage Reconstruction of Scalp after Full-Thickness Oncologic Defects Using a Dermal Regeneration Template (Integra).

Authors:  Barbara De Angelis; Pietro Gentile; Eleonora Tati; Davide J Bottini; Ilaria Bocchini; Fabrizio Orlandi; Giampiero Pepe; Chiara Di Segni; Giulio Cervelli; Valerio Cervelli
Journal:  Biomed Res Int       Date:  2015-11-16       Impact factor: 3.411

9.  Integra-based Reconstruction of Large Scalp Wounds: A Case Report and Systematic Review of the Literature.

Authors:  Maxwell B Johnson; Alex K Wong
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-10-24

10.  An algorithm for one-stage malignant oncologic scalp reconstruction.

Authors:  Yuqiu Zhou; Zhenhua Jiang; Chao Li; Yongcong Cai; Ronghao Sun; Chunyan Shui; Changming An; Zhengqi Tang; Jianfeng Sheng; Dingrong Liu; Dingfen Zeng; Jian Jiang; Guiquan Zhu; Shaoxin Wang
Journal:  Ann Transl Med       Date:  2020-04
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