Literature DB >> 1954078

Circadian changes in estimated hepatic blood flow in healthy subjects.

B Lemmer1, G Nold.   

Abstract

Intravenous injections of indocyanine green (ICG) were given to 10 healthy supine subjects at 02.00, 08.00, 14.00 and 20.00 h. ICG plasma half-life, plasma clearance and estimated hepatic blood flow (EHBF), but not volume of distribution, varied significantly with time of day with EHBF being greatest at 08.00 h. This circadian rhythm in EHBF should be considered when evaluating the kinetics of high-clearance drugs at different times of day.

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Year:  1991        PMID： 1954078      PMCID： PMC1368643          DOI： 10.1111/j.1365-2125.1991.tb03964.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  7 in total

1.  The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function.

Authors:  J CAESAR; S SHALDON; L CHIANDUSSI; L GUEVARA; S SHERLOCK
Journal:  Clin Sci       Date:  1961-08       Impact factor: 6.124

Review 2.  Chronopharmacokinetics and chronopharmacodynamics of cardiovascular active drugs. Propranolol, organic nitrates, nifedipine.

Authors:  B Lemmer; B Scheidel; S Behne
Journal:  Ann N Y Acad Sci       Date:  1991       Impact factor: 5.691

3.  Circadian changes in the pharmacokinetics and cardiovascular effects of oral propranolol in healthy subjects.

Authors:  B Langner; B Lemmer
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

4.  Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis.

Authors:  L S Olanoff; T Walle; T D Cowart; U K Walle; M J Oexmann; E C Conradi
Journal:  Clin Pharmacol Ther       Date:  1986-10       Impact factor: 6.875

5.  Effect of food on hepatic blood flow: implications in the "food effect" phenomenon.

Authors:  C K Svensson; D J Edwards; P M Mauriello; S H Barde; A C Foster; R A Lanc; E Middleton; D Lalka
Journal:  Clin Pharmacol Ther       Date:  1983-09       Impact factor: 6.875

6.  Physiological and pharmacological variability in estimated hepatic blood flow in man.

Authors:  T K Daneshmend; L Jackson; C J Roberts
Journal:  Br J Clin Pharmacol       Date:  1981-05       Impact factor: 4.335

7.  Nifedipine increases and glyceryl trinitrate decreases apparent liver blood flow in normal subjects.

Authors:  J Feely
Journal:  Br J Clin Pharmacol       Date:  1984-01       Impact factor: 4.335
  7 in total
  33 in total

1.  [Circadian rhythms and clinical pharmacology].

Authors:  B Lemmer
Journal:  Internist (Berl)       Date:  2004-09       Impact factor: 0.743

2.  Appropriateness of timing of drug administration in electronic prescriptions.

Authors:  Arwa Hassan; Walter E Haefeli
Journal:  Pharm World Sci       Date:  2010-01-10

Review 3.  Chronopharmacokinetics. Current status.

Authors:  B Bruguerolle
Journal:  Clin Pharmacokinet       Date:  1998-08       Impact factor: 6.447

4.  Indirect pharmacodynamic models for responses with circadian removal.

Authors:  Vivaswath S Ayyar; Wojciech Krzyzanski; William J Jusko
Journal:  J Pharmacokinet Pharmacodyn       Date:  2019-01-29       Impact factor: 2.745

5.  Clinical aspects of indocyanine green pharmacokinetics following portal vein administration.

Authors:  S Nishi; M Shindo; J Abe; A Asada
Journal:  Br J Clin Pharmacol       Date:  1998-01       Impact factor: 4.335

Review 6.  Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics.

Authors:  Joana Bicker; Gilberto Alves; Amílcar Falcão; Ana Fortuna
Journal:  Br J Pharmacol       Date:  2020-03-20       Impact factor: 8.739

7.  The effect of age on diurnal variation in the pharmacokinetics of propranolol in hypertensive subjects.

Authors:  T Shiga; A Fujimura; T Tateishi; K Ohashi; A Ebihara
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

Review 8.  Chronopharmacokinetics. Are they clinically relevant?

Authors:  B Lemmer; B Bruguerolle
Journal:  Clin Pharmacokinet       Date:  1994-06       Impact factor: 6.447

9.  Absence of circadian variation in the pharmacokinetics of lopinavir/ritonavir given as a once daily dosing regimen in HIV-1-infected patients.

Authors:  R P G van Heeswijk; M Bourbeau; I Seguin; P Giguere; G E Garber; D W Cameron
Journal:  Br J Clin Pharmacol       Date:  2005-04       Impact factor: 4.335

10.  The effect of oxprenolol dosage time on its pharmacokinetics and haemodynamic effects during exercise in man.

Authors:  R Koopmans; B Oosterhuis; J M Karemaker; J Wemer; C J van Boxtel
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953
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