Literature DB >> 1953773

The solution conformation of the Le chi group.

M R Wormald1, C J Edge, R A Dwek.   

Abstract

The solution conformation of the non-reducing terminal Gal beta 1----4 (Fuc alpha 1----3)GlcNAc (Lewis X or Le chi) group in the oligosaccharide Lacto-N-fucopentaose (LNFP) III has been determined by high resolution 1H NMR spectroscopy and semi-empirical quantum mechanical calculations. The two methods give the same single conformer for the Le chi group showing close packing of the Gal and Fuc rings. The metal binding properties and homotypic oligomer formation of LNFP III have also been investigated by NMR spectroscopy. No evidence for metal binding or high-affinity homotypic oligomer formation has been found.

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Year:  1991        PMID： 1953773     DOI： 10.1016/s0006-291x(05)81325-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

1.  Application of homonuclear 3D NMR experiments and 1D analogs to study the conformation of sialyl Lewis(x) bound to E-selectin.

Authors:  K Scheffler; J R Brisson; R Weisemann; J L Magnani; W T Wong; B Ernst; T Peters
Journal:  J Biomol NMR       Date:  1997-06       Impact factor: 2.835

2.  Conformation of the oligosaccharide chain of G(M1) ganglioside in a carbohydrate-enriched surface.

Authors:  P Brocca; P Berthault; S Sonnino
Journal:  Biophys J       Date:  1998-01       Impact factor: 4.033

Review 3.  Understanding carbohydrate-carbohydrate interactions by means of glyconanotechnology.

Authors:  Jesus M de la Fuente; Soledad Penadés
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916

Review 4.  Carbohydrate-to-carbohydrate interaction, through glycosynapse, as a basis of cell recognition and membrane organization.

Authors:  Senitiroh Hakomori
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916

5.  Analysis of GM3-Gg3 interaction using clustered gycoconjugate models constructed from glycolipid monolayers and artificial glycoconjugate polymers.

Authors:  Kazunori Matsuura; Kazukiyo Kobayashi
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916

6.  Cellular interaction through LewisX cluster: theoretical studies.

Authors:  Yun Luo; Florent Barbault; Chafika Gourmala; Yongmin Zhang; François Maurel; Yongzhou Hu; Bo Tao Fan
Journal:  J Mol Model       Date:  2008-07-11       Impact factor: 1.810

7.  First synthesis of two deoxy Lewis(x) pentaosyl glycosphingolipids.

Authors:  Yun Luo; Chafika Gourmala; Dengxiang Dong; Florent Barbault; Botao Fan; Yongzhou Hu; Yongmin Zhang
Journal:  Glycoconj J       Date:  2007-11-01       Impact factor: 2.916

8.  Conformations and internal mobility of a glycopeptide derived from bromelain using molecular dynamics simulations and NOESY analysis.

Authors:  J P Lommerse; L M Kroon-Batenburg; J Kroon; J P Kamerling; J F Vliegenthart
Journal:  J Biomol NMR       Date:  1995-07       Impact factor: 2.835

9.  alpha 1,3-Fucosylation of branched blood group I-type oligo-(N-acetyllactosamino)glycans by human milk transferases is restricted to distal N-acetyllactosamine units: the resulting isomers are separated by WGA-agarose chromatography.

Authors:  R Niemelä; J Natunen; E Brotherus; A Saarikangas; O Renkonen
Journal:  Glycoconj J       Date:  1995-02       Impact factor: 2.916
  9 in total

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