BACKGROUND: To determine if the pathology of small (< or = 4 cm) solid renal tumors can be predicted from findings on multidetector CT. METHODS: This retrospective study included 46 patients (median age, 60 years; range, 32-91 years; 27 males, 19 females) with 47 tumors who underwent triphasic renal CT with pathology correlation. Two radiologists reviewed CT studies blinded to pathology results and recorded the morphologic and enhancement features of the tumors. RESULTS: The 47 tumors (median diameter, 2.5 cm; range, 0.6-4.0 cm) included: 26 (55%) clear cell renal cell carcinomas; 9 (19%) oncocytomas; 7 (15%) papillary renal cell carcinomas; 2 (4%) chromophobe renal cell carcinomas; 2 (4%) inflammatory pseudotumors; and 1 (2%) angiomyolipoma with minimal fat. Amongst the three commonest tumors, heterogeneity was seen in 23/26 (88%) clear cell renal cell carcinomas, 6/9 (67%) oncocytomas, and 2/7 (29%) papillary renal cell cancer. Median (minimum-maximum) absolute nephrographic phase enhancement (nephrographic minus unenhanced phase) was: clear cell renal cell carcinomas 65 HU (34-120), oncocytomas 80 HU (51-111), and papillary renal cell carcinomas 16 HU (7-32). CONCLUSION: Absolute nephrographic phase enhancement of < or = 32 HU distinguished papillary renal cell carcinomas from clear cell renal cell carcinomas and oncocytomas.
BACKGROUND: To determine if the pathology of small (< or = 4 cm) solid renal tumors can be predicted from findings on multidetector CT. METHODS: This retrospective study included 46 patients (median age, 60 years; range, 32-91 years; 27 males, 19 females) with 47 tumors who underwent triphasic renal CT with pathology correlation. Two radiologists reviewed CT studies blinded to pathology results and recorded the morphologic and enhancement features of the tumors. RESULTS: The 47 tumors (median diameter, 2.5 cm; range, 0.6-4.0 cm) included: 26 (55%) clear cell renal cell carcinomas; 9 (19%) oncocytomas; 7 (15%) papillary renal cell carcinomas; 2 (4%) chromophobe renal cell carcinomas; 2 (4%) inflammatory pseudotumors; and 1 (2%) angiomyolipoma with minimal fat. Amongst the three commonest tumors, heterogeneity was seen in 23/26 (88%) clear cell renal cell carcinomas, 6/9 (67%) oncocytomas, and 2/7 (29%) papillary renal cell cancer. Median (minimum-maximum) absolute nephrographic phase enhancement (nephrographic minus unenhanced phase) was: clear cell renal cell carcinomas 65 HU (34-120), oncocytomas 80 HU (51-111), and papillary renal cell carcinomas 16 HU (7-32). CONCLUSION: Absolute nephrographic phase enhancement of < or = 32 HU distinguished papillary renal cell carcinomas from clear cell renal cell carcinomas and oncocytomas.
Authors: Kathleen Nguyen; Nicola Schieda; Nick James; Matthew D F McInnes; Mark Wu; Rebecca E Thornhill Journal: Eur Radiol Date: 2020-09-10 Impact factor: 5.315
Authors: Phillip M Pierorazio; Elias S Hyams; Salina Tsai; Zhaoyong Feng; Bruce J Trock; Jeffrey K Mullins; Pamela T Johnson; Elliot K Fishman; Mohamad E Allaf Journal: Urology Date: 2013-04-17 Impact factor: 2.649