Literature DB >> 19533818

Anabolic steroid-induced cardiomyopathy underlying acute liver failure in a young bodybuilder.

Miguel Bispo1, Ana Valente, Rosário Maldonado, Rui Palma, Helena Glória, João Nóbrega, Paula Alexandrino.   

Abstract

Heart failure may lead to subclinical circulatory disturbances and remain an unrecognized cause of ischemic liver injury. We present the case of a previously healthy 40-year-old bodybuilder, referred to our Intensive-Care Unit of Hepatology for treatment of severe acute liver failure, with the suspicion of toxic hepatitis associated with anabolic steroid abuse. Despite the absence of symptoms and signs of congestive heart failure at admission, an anabolic steroid-induced dilated cardiomyopathy with a large thrombus in both ventricles was found to be the underlying cause of the liver injury. Treatment for the initially unrecognized heart failure rapidly restored liver function to normal. To our knowledge, this is the first reported case of severe acute liver failure due to an unrecognized anabolic steroid-induced cardiomyopathy. Awareness of this unique presentation will allow for prompt treatment of this potentially fatal cause of liver failure.

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Year:  2009        PMID: 19533818      PMCID: PMC2699014          DOI: 10.3748/wjg.15.2920

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  18 in total

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Journal:  World J Gastroenterol       Date:  2008-07-28       Impact factor: 5.742

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  12 in total

Review 1.  Doping with anabolic androgenic steroids (AAS): Adverse effects on non-reproductive organs and functions.

Authors:  Eberhard Nieschlag; Elena Vorona
Journal:  Rev Endocr Metab Disord       Date:  2015-09       Impact factor: 6.514

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4.  Cardiomyopathy and heart failure secondary to anabolic-androgen steroid abuse.

Authors:  Onyedika J Ilonze; Chioma O Enyi; Chibuzo C Ilonze
Journal:  Proc (Bayl Univ Med Cent)       Date:  2022-03-17

5.  Performance-Enhancing Substance Use and Sexual Risk Behaviors among U.S. Men: Results from a Prospective Cohort Study.

Authors:  Kyle T Ganson; Dylan B Jackson; Alexander Testa; Pamela M Murnane; Jason M Nagata
Journal:  J Sex Res       Date:  2021-12-03

6.  Anabolic androgenic steroid-induced acute myocardial infarction with multiorgan failure.

Authors:  Frederick J Flo; Obiajulu Kanu; Mohamed Teleb; Yuefeng Chen; Tariq Siddiqui
Journal:  Proc (Bayl Univ Med Cent)       Date:  2018-05-15

7.  Anabolic steroids abuse-induced cardiomyopathy and ischaemic stroke in a young male patient.

Authors:  Reham Mohammed Shamloul; Ahmed Fathy Aborayah; Assem Hashad; Foad Abd-Allah
Journal:  BMJ Case Rep       Date:  2014-02-26

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Journal:  Curr Cardiol Rev       Date:  2021

9.  Performance-Enhancing Drugs Abuse Caused Cardiomyopathy and Acute Hepatic Injury in a Young Bodybuilder.

Authors:  Cheng Li; Binay Kumar Adhikari; Lu Gao; Shuai Zhang; Quan Liu; Yonggang Wang; Jian Sun
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10.  Echocardiographic findings in power athletes abusing anabolic androgenic steroids.

Authors:  Behzad Hajimoradi; Hashem Kazerani
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