Literature DB >> 19532917

Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: the effect of charge on drug distribution in solid tumour models.

Nicole S Bryce1, Jenny Z Zhang, Renee M Whan, Natsuho Yamamoto, Trevor W Hambley.   

Abstract

The penetration of anthraquinones and their platinum complexes into cancer cell spheroids reveals that they model well the distribution of such compounds in solid tumours and that the proportion of the compound that accumulates deep in the spheroid is inversely related to the rate of cellular uptake which is affected by the charge of the compound.

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Year:  2009        PMID： 19532917     DOI： 10.1039/b902415h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  17 in total

1.  Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure-activity relationship modeling.

Authors:  Paola Gramatica; Ester Papa; Mara Luini; Elena Monti; Marzia B Gariboldi; Mauro Ravera; Elisabetta Gabano; Luca Gaviglio; Domenico Osella
Journal:  J Biol Inorg Chem       Date:  2010-06-06       Impact factor: 3.358

Review 2.  Nanoscale drug delivery systems for enhanced drug penetration into solid tumors: current progress and opportunities.

Authors:  Carolyn L Waite; Charles M Roth
Journal:  Crit Rev Biomed Eng       Date:  2012

Review 3.  Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy.

Authors:  Geeta Mehta; Amy Y Hsiao; Marylou Ingram; Gary D Luker; Shuichi Takayama
Journal:  J Control Release       Date:  2012-05-18       Impact factor: 9.776

4.  Synthesis and biological evaluation of water-soluble progesterone-conjugated probes for magnetic resonance imaging of hormone related cancers.

Authors:  Preeti A Sukerkar; Keith W MacRenaris; Taryn R Townsend; Roshan A Ahmed; Joanna E Burdette; Thomas J Meade
Journal:  Bioconjug Chem       Date:  2011-10-05       Impact factor: 4.774

Review 5.  Mass spectrometry imaging of therapeutics from animal models to three-dimensional cell cultures.

Authors:  Xin Liu; Amanda B Hummon
Journal:  Anal Chem       Date:  2015-07-02       Impact factor: 6.986

6.  Quantitative Proteomic and Phosphoproteomic Comparison of 2D and 3D Colon Cancer Cell Culture Models.

Authors:  Xiaoshan Yue; Jessica K Lukowski; Eric M Weaver; Susan B Skube; Amanda B Hummon
Journal:  J Proteome Res       Date:  2016-10-10       Impact factor: 4.466

7.  Os(II)-Bridged Polyarginine Conjugates: The Additive Effects of Peptides in Promoting or Preventing Permeation in Cells and Multicellular Tumor Spheroids.

Authors:  Karmel S Gkika; Sara Noorani; Naomi Walsh; Tia E Keyes
Journal:  Inorg Chem       Date:  2021-05-12       Impact factor: 5.165

8.  Intracellular trafficking as a determinant of AS-DACA cytotoxicity in rhabdomyosarcoma cells.

Authors:  Steven J Wolf; Tony Huynh; Nicole S Bryce; Trevor W Hambley; Laurence P G Wakelin; Bernard W Stewart; Daniel R Catchpoole
Journal:  BMC Cell Biol       Date:  2011-08-24       Impact factor: 4.241

9.  Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing.

Authors:  Xue Gong; Chao Lin; Jian Cheng; Jiansheng Su; Hang Zhao; Tianlin Liu; Xuejun Wen; Peng Zhao
Journal:  PLoS One       Date:  2015-06-19       Impact factor: 3.240

10.  The role of tumor tissue architecture in treatment penetration and efficacy: an integrative study.

Authors:  Katarzyna A Rejniak; Veronica Estrella; Tingan Chen; Allison S Cohen; Mark C Lloyd; David L Morse
Journal:  Front Oncol       Date:  2013-05-10       Impact factor: 6.244
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