Literature DB >> 19524648

Bioactive constituents from the stems of Dalbergia parviflora.

Uraiwan Songsiang1, Suchana Wanich, Siripit Pitchuanchom, Siwames Netsopa, Komphet Uanporn, Chavi Yenjai.   

Abstract

From the stems of Dalbergia parviflora, three known flavonoids, six known isoflavonoids, a new isoflavone, dalparvone (2) and a new cinnamyl derivative, dalparvinene (6) were isolated and characterized. Isoflavan 3 exhibited strong cytotoxicity against KB and NCI-H187 cell lines with IC(50) values of 0.53 and 2.04 microg/ml, respectively. Compound 6 demonstrated strong cytotoxicity against NCI-H187 with an IC(50) value of 1.46 microg/ml. Compounds 4 and 6 possessed moderate cytotoxicity against KB cells with IC(50) values of 6.78 and 9.89 microg/ml, respectively. In addition, 2 exhibited moderate antiplasmodial activity with an IC(50) value of 8.19 microg/ml.

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Year:  2009        PMID： 19524648     DOI： 10.1016/j.fitote.2009.06.002

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  6 in total

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Journal:  Sci Pharm       Date:  2012-02-27

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Journal:  PLoS One       Date:  2015-07-17       Impact factor: 3.240

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Journal:  Evid Based Complement Alternat Med       Date:  2017-07-03       Impact factor: 2.629

Review 5.  Promising Antimycobacterial Activities of Flavonoids against Mycobacterium sp. Drug Targets: A Comprehensive Review.

Authors:  Ali A Rabaan; Saad Alhumaid; Hawra Albayat; Mohammed Alsaeed; Fadwa S Alofi; Mawaheb H Al-Howaidi; Safaa A Turkistani; Salah M Alhajri; Hejji E Alahmed; Abdulwahab B Alzahrani; Mutaib M Mashraqi; Sara Alwarthan; Mashael Alhajri; Fatimah S Alshahrani; Souad A Almuthree; Roua A Alsubki; Abdulmonem A Abuzaid; Mubarak Alfaresi; Mona A Al Fares; Abbas Al Mutair
Journal:  Molecules       Date:  2022-08-22       Impact factor: 4.927

6.  Structural modification of olibergin A, an isoflavonoid, from Dalbergia stipulacea Roxb. and its cytotoxicity.

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  6 in total

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