Literature DB >> 19520314

Relevance of quantum mechanics on some aspects of ion channel function.

Sisir Roy1, Rodolfo Llinás.   

Abstract

Mathematical modeling of ionic diffusion along K ion channels indicates that such diffusion is oscillatory, at the weak non-Markovian limit. This finding leads us to derive a Schrödinger-Langevin equation for this kind of system within the framework of stochastic quantization. The Planck's constant is shown to be relevant to the Lagrangian action at the level of a single ion channel. This sheds new light on the issue of applicability of quantum formalism to ion channel dynamics and to the physical constraints of the selectivity filter.

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Year:  2009        PMID: 19520314      PMCID: PMC2862977          DOI: 10.1016/j.crvi.2008.11.009

Source DB:  PubMed          Journal:  C R Biol        ISSN: 1631-0691            Impact factor:   1.583


  7 in total

1.  Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.

Authors:  Y Zhou; J H Morais-Cabral; A Kaufman; R MacKinnon
Journal:  Nature       Date:  2001-11-01       Impact factor: 49.962

2.  Capillary condensation in atomic scale friction: how water acts like a glue.

Authors:  K B Jinesh; J W M Frenken
Journal:  Phys Rev Lett       Date:  2006-04-27       Impact factor: 9.161

3.  Symmetric free-energy-based multicomponent lattice Boltzmann method.

Authors:  Qun Li; A J Wagner
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2007-09-04

4.  The components of membrane conductance in the giant axon of Loligo.

Authors:  A L HODGKIN; A F HUXLEY
Journal:  J Physiol       Date:  1952-04       Impact factor: 5.182

5.  The structure of the potassium channel: molecular basis of K+ conduction and selectivity.

Authors:  D A Doyle; J Morais Cabral; R A Pfuetzner; A Kuo; J M Gulbis; S L Cohen; B T Chait; R MacKinnon
Journal:  Science       Date:  1998-04-03       Impact factor: 47.728

6.  Liquid-vapor oscillations of water in hydrophobic nanopores.

Authors:  Oliver Beckstein; Mark S P Sansom
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-09       Impact factor: 11.205

7.  Beyond the diffusion limit: Water flow through the empty bacterial potassium channel.

Authors:  Sapar M Saparov; Peter Pohl
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-19       Impact factor: 11.205

  7 in total
  3 in total

Review 1.  The Soul, as an Uninhibited Mental Activity, is Reduced into Consciousness by Rules of Quantum Physics.

Authors:  Mehmet Emin Ceylan; Aslıhan Dönmez; Barış Önen Ünsalver; Alper Evrensel; Fatma Duygu Kaya Yertutanol
Journal:  Integr Psychol Behav Sci       Date:  2017-12

Review 2.  Bacterial intelligence: imitation games, time-sharing, and long-range quantum coherence.

Authors:  Sarangam Majumdar; Sukla Pal
Journal:  J Cell Commun Signal       Date:  2017-05-17       Impact factor: 5.782

3.  Information transmission in microbial and fungal communication: from classical to quantum.

Authors:  Sarangam Majumdar; Sukla Pal
Journal:  J Cell Commun Signal       Date:  2018-02-23       Impact factor: 5.782

  3 in total

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