Literature DB >> 19520027

Five misconceptions in cancer diagnosis.

William Hamilton1.   

Abstract

Much investment has been put into facilities for early cancer diagnosis. It is difficult to know how successful this investment has been. New facilities for rapid investigation in the UK have not reduced mortality, and may cause delays in diagnosis of patients with low-risk, or atypical, symptoms. In part, the failure of new facilities to translate into mortality benefits can be explained by five misconceptions. These are described, along with suggested research and organisational remedies. The first misconception is that cancer is diagnosed in hospitals. Consequently, secondary care data have been used to drive primary care decisions. Second, GPs are thought to be poor at cancer diagnosis, yet the type of education on offer to improve this may not be what is needed. Third, symptomatic cancer diagnosis has been downgraded in importance with the introduction of screening, yet screening identifies only a small minority of cancers. Fourth, pressure is put on GPs to make referrals for those with an individual high risk of cancer - disenfranchising those with 'low-risk but not no-risk' symptoms. Finally, considerable nihilism exists about the value of early diagnosis, despite considerable observational evidence that earlier diagnosis of symptomatic cancer is beneficial.

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Year:  2009        PMID: 19520027      PMCID: PMC2688046          DOI: 10.3399/bjgp09X420860

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN: 0960-1643            Impact factor:   5.386


  36 in total

1.  Pathways to the diagnosis of prostate cancer in a British city. A population-based study.

Authors:  Jacqueline Barrett; William Hamilton
Journal:  Scand J Urol Nephrol       Date:  2005

2.  Negative chest X-rays in primary care patients with lung cancer.

Authors:  Sally Stapley; Deborah Sharp; William Hamilton
Journal:  Br J Gen Pract       Date:  2006-08       Impact factor: 5.386

3.  Clinical features of primary brain tumours: a case-control study using electronic primary care records.

Authors:  William Hamilton; David Kernick
Journal:  Br J Gen Pract       Date:  2007-09       Impact factor: 5.386

4.  Diagnosis of colorectal cancer in primary care: the evidence base for guidelines.

Authors:  William Hamilton; Deborah Sharp
Journal:  Fam Pract       Date:  2004-02       Impact factor: 2.267

5.  Impact of the '2 week wait' on referrals to breast units in the UK.

Authors:  P Sauven
Journal:  Breast       Date:  2002-06       Impact factor: 4.380

6.  The effects of population-based faecal occult blood test screening upon emergency colorectal cancer admissions in Coventry and north Warwickshire.

Authors:  S J Goodyear; E Leung; A Menon; S Pedamallu; N Williams; L S Wong
Journal:  Gut       Date:  2007-11-29       Impact factor: 23.059

7.  The mortality of colorectal cancer in relation to the initial symptom at presentation to primary care and to the duration of symptoms: a cohort study using medical records.

Authors:  S Stapley; T J Peters; D Sharp; W Hamilton
Journal:  Br J Cancer       Date:  2006-10-24       Impact factor: 7.640

8.  Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients.

Authors:  N G Hurst; D D Stocken; S Wilson; C Keh; M J O Wakelam; T Ismail
Journal:  Br J Cancer       Date:  2007-10-02       Impact factor: 7.640

9.  Pathways to the diagnosis of lung cancer in the UK: a cohort study.

Authors:  Jacqueline Barrett; William Hamilton
Journal:  BMC Fam Pract       Date:  2008-05-18       Impact factor: 2.497

10.  The importance of anaemia in diagnosing colorectal cancer: a case-control study using electronic primary care records.

Authors:  W Hamilton; R Lancashire; D Sharp; T J Peters; K K Cheng; T Marshall
Journal:  Br J Cancer       Date:  2008-01-22       Impact factor: 7.640

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  48 in total

1.  Primary care delays in diagnosing cancer: what is causing them and what can we do about them?

Authors:  Thomas Round; Liz Steed; Judith Shankleman; Liam Bourke; Liliana Risi
Journal:  J R Soc Med       Date:  2013-10-09       Impact factor: 5.344

2.  Early diagnosis of cancer--the role of general practice.

Authors:  Peter Vedsted; Frede Olesen
Journal:  Scand J Prim Health Care       Date:  2009       Impact factor: 2.581

3.  Quality deviations in cancer diagnosis: prevalence and time to diagnosis in general practice.

Authors:  Henry Jensen; Aase Nissen; Peter Vedsted
Journal:  Br J Gen Pract       Date:  2014-02       Impact factor: 5.386

4.  Impact of travel time and rurality on presentation and outcomes of symptomatic colorectal cancer: a cross-sectional cohort study in primary care.

Authors:  Peninah Murage; Peter Murchie; Max Bachmann; Michael Crawford; Andy Jones
Journal:  Br J Gen Pract       Date:  2017-06-05       Impact factor: 5.386

5.  Predictive values of GPs' suspicion of serious disease: a population-based follow-up study.

Authors:  Peter Hjertholm; Grete Moth; Mads Lind Ingeman; Peter Vedsted
Journal:  Br J Gen Pract       Date:  2014-06       Impact factor: 5.386

6.  Possible missed opportunities for diagnosing colorectal cancer in Dutch primary care: a multimethods approach.

Authors:  Daan Brandenbarg; Feikje Groenhof; Ilse M Siewers; Anna van der Voort; Fiona M Walter; Annette J Berendsen
Journal:  Br J Gen Pract       Date:  2017-12-04       Impact factor: 5.386

7.  How does the thought of cancer arise in a general practice consultation? Interviews with GPs.

Authors:  May-Lill Johansen; Knut Arne Holtedahl; Carl Edvard Rudebeck
Journal:  Scand J Prim Health Care       Date:  2012-07-02       Impact factor: 2.581

8.  Auditing the diagnosis of cancer in primary care: the experience in Scotland.

Authors:  P Baughan; B O'Neill; E Fletcher
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

9.  The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients.

Authors:  W Hamilton
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

10.  The risk of colorectal cancer with symptoms at different ages and between the sexes: a case-control study.

Authors:  William Hamilton; Robert Lancashire; Debbie Sharp; Tim J Peters; Kk Cheng; Tom Marshall
Journal:  BMC Med       Date:  2009-04-17       Impact factor: 8.775

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