Literature DB >> 19519576

Recent trends in oral drug delivery: a review.

Himanshu Gupta1, Dinesh Bhandari, Aarti Sharma.   

Abstract

There are many ways to deliver drugs into the body, viz oral (through swallowing), sub mucosal (through buccal and sublingual mucosa), parenteral (through injection), transdermal (through skin), pulmonary (through inhalation) etc. Among these deliveries oral delivery (by swallowing) is widely accepted. In oral drug delivery, many scientific challenges and breakthrough technologies are required to generate novel dosage forms raising drug delivery to higher level. Some are self emulsifying systems, solid self nanoemulsion, polymeric micelles, spray freezing, pH controlled systems, time delayed system, osmotic pumps, prodrugs etc. This paper reviews recent patents, technologies and products with their importance, manufacturing and novel approaches implemented till date to overcome the challenges in oral drug delivery systems.

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Year:  2009        PMID: 19519576     DOI: 10.2174/187221109788452267

Source DB:  PubMed          Journal:  Recent Pat Drug Deliv Formul        ISSN: 1872-2113


  11 in total

1.  Role of nanoparticle size, shape and surface chemistry in oral drug delivery.

Authors:  Amrita Banerjee; Jianping Qi; Rohan Gogoi; Jessica Wong; Samir Mitragotri
Journal:  J Control Release       Date:  2016-07-30       Impact factor: 9.776

2.  Sustained epidermal powder drug delivery via skin microchannels.

Authors:  Yan Cao; Prateek Kakar; Md Nazir Hossen; Mei X Wu; Xinyuan Chen
Journal:  J Control Release       Date:  2017-01-27       Impact factor: 9.776

3.  Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization.

Authors:  Sana Javed; Amjad Hussain; Pervaiz Akhtar Shah; Syed Atif Raza; Ubaid Ullah Anwer; Rahat Shamim; Fatima Rasool; Muhammad Ahsan Hafiz; Nadeem Irfan Bukhari
Journal:  AAPS PharmSciTech       Date:  2022-06-02       Impact factor: 3.246

4.  QbD-Enabled Development of Novel Stimuli-Responsive Gastroretentive Systems of Acyclovir for Improved Patient Compliance and Biopharmaceutical Performance.

Authors:  Bhupinder Singh; Anterpreet Kaur; Shashi Dhiman; Babita Garg; Rajneet Kaur Khurana; Sarwar Beg
Journal:  AAPS PharmSciTech       Date:  2015-08-04       Impact factor: 3.246

5.  Novel cationic supersaturable nanomicellar systems of raloxifene hydrochloride with enhanced biopharmaceutical attributes.

Authors:  Atul Jain; Rajpreet Kaur; Sarwar Beg; Varun Kushwah; Sanyog Jain; Bhupinder Singh
Journal:  Drug Deliv Transl Res       Date:  2018-06       Impact factor: 4.617

6.  Development and optimization of osmotically controlled asymmetric membrane capsules for delivery of solid dispersion of lycopene.

Authors:  Nitin Jain; Rashmi Sareen; Neeraj Mahindroo; K L Dhar
Journal:  ScientificWorldJournal       Date:  2014-01-29

Review 7.  Nanotechnology Based Approaches for Enhancing Oral Bioavailability of Poorly Water Soluble Antihypertensive Drugs.

Authors:  Mayank Sharma; Rajesh Sharma; Dinesh Kumar Jain
Journal:  Scientifica (Cairo)       Date:  2016-04-30

8.  Computational Modeling of Drug Dissolution in the Human Stomach.

Authors:  Jung Hee Seo; Rajat Mittal
Journal:  Front Physiol       Date:  2022-01-10       Impact factor: 4.566

9.  Development and Evaluation of Novel Self-Nanoemulsifying Drug Delivery Systems Based on a Homolipid from Capra hircus and Its Admixtures with Melon Oil for the Delivery of Indomethacin.

Authors:  Nicholas C Obitte; Kenneth C Ofokansi; Franklin C Kenechukwu
Journal:  J Pharm (Cairo)       Date:  2014-03-20

Review 10.  On-Demand Drug Delivery Systems Using Nanofibers.

Authors:  Baljinder Singh; Kibeom Kim; Myoung-Hwan Park
Journal:  Nanomaterials (Basel)       Date:  2021-12-16       Impact factor: 5.076

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