PURPOSE: The purpose of this study is to assess sexual function among patients with clinically localized prostate cancer referred for radiotherapy and to prospectively evaluate the effect of radiotherapy on sexual function, using the Brief Sexual Function Inventory (BSFI). MATERIALS AND METHODS: A descriptive study, approved by the local research ethics committee, was prospectively conducted. At baseline, patients were asked to complete a self-administered BSFI, along with other questionnaires describing their clinical condition. Patients with normal erection at baseline were asked to complete a follow-up BSFI at 6, 12, and 24 months postradiotherapy. The collected data was analyzed using the SAS software. RESULTS: The study accrued a total of 117 eligible patients. The mean age was 66 years. Forty-two patients (35.9%) were considered to have erectile dysfunction (ED) at baseline. They were older and more likely on one or more medications affecting potency, compared with those with normal erectile function. They had a consistently lower mean score for all the five domains of BSFI and considered sexual activity less important. Of the 75 patients reporting normal erectile function at baseline, 61 completed a follow-up BSFI questionnaire. Among the 61 patients, 52 underwent radiotherapy with external beam radiotherapy or brachytherapy. Mean scores for all the BSFI domains declined after radiotherapy, suggesting that radiotherapy adversely affected not only erectile function but also other aspects of sexual function including sexual drive and ejaculation. CONCLUSION: Among the patients with clinically localized prostate cancer referred for radiotherapy, sexual dysfunction was prevalent with 35.9% reporting ED at presentation. Radiotherapy adversely affected all aspects of sexual function.
PURPOSE: The purpose of this study is to assess sexual function among patients with clinically localized prostate cancer referred for radiotherapy and to prospectively evaluate the effect of radiotherapy on sexual function, using the Brief Sexual Function Inventory (BSFI). MATERIALS AND METHODS: A descriptive study, approved by the local research ethics committee, was prospectively conducted. At baseline, patients were asked to complete a self-administered BSFI, along with other questionnaires describing their clinical condition. Patients with normal erection at baseline were asked to complete a follow-up BSFI at 6, 12, and 24 months postradiotherapy. The collected data was analyzed using the SAS software. RESULTS: The study accrued a total of 117 eligible patients. The mean age was 66 years. Forty-two patients (35.9%) were considered to have erectile dysfunction (ED) at baseline. They were older and more likely on one or more medications affecting potency, compared with those with normal erectile function. They had a consistently lower mean score for all the five domains of BSFI and considered sexual activity less important. Of the 75 patients reporting normal erectile function at baseline, 61 completed a follow-up BSFI questionnaire. Among the 61 patients, 52 underwent radiotherapy with external beam radiotherapy or brachytherapy. Mean scores for all the BSFI domains declined after radiotherapy, suggesting that radiotherapy adversely affected not only erectile function but also other aspects of sexual function including sexual drive and ejaculation. CONCLUSION: Among the patients with clinically localized prostate cancer referred for radiotherapy, sexual dysfunction was prevalent with 35.9% reporting ED at presentation. Radiotherapy adversely affected all aspects of sexual function.
Authors: C T Chen; R K Valicenti; J Lu; T Derose; A P Dicker; S E Strup; S G Mulholland; I H Hirsch; D E McGinnis; L G Gomella Journal: Int J Radiat Oncol Biol Phys Date: 2001-07-01 Impact factor: 7.038
Authors: Marigdalia K Ramirez-Fort; Marc J Rogers; Roberto Santiago; Sean S Mahase; Melissa Mendez; Yi Zheng; Xiang Kong; James A Kashanian; M Junaid Niaz; Shearwood McClelland; Xiaodong Wu; Neil H Bander; Peter Schlegel; John P Mulhall; Christopher S Lange Journal: Rep Pract Oncol Radiother Date: 2020-03-19
Authors: Jennifer R Rider; Kathryn M Wilson; Jennifer A Sinnott; Rachel S Kelly; Lorelei A Mucci; Edward L Giovannucci Journal: Eur Urol Date: 2016-03-28 Impact factor: 20.096
Authors: Damiano Pizzol; Tao Xiao; Lee Smith; Guillermo F López Sánchez; Andrea Garolla; Christopher Parris; Yvonne Barnett; Petre Cristian Ilie; Pinar Soysal; Jae Il Shin; Mark A Tully; Lin Yang; Nicola Veronese; Igor Grabovac Journal: Br J Gen Pract Date: 2021-04-29 Impact factor: 5.386