Literature DB >> 19506059

H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.

Kunihiko Nishino1, Mitsuko Hayashi-Nishino, Akihito Yamaguchi.   

Abstract

Screening of Salmonella mutants for the ability to increase beta-lactam resistance has led to the identification of a mutation in hns, which codes for the histone-like nucleoid structuring protein (H-NS). In this study, we report that H-NS modulates multidrug resistance through repression of the genes that encode the AcrEF multidrug efflux pump in Salmonella enterica serovar Typhimurium.

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Year:  2009        PMID： 19506059      PMCID： PMC2715579          DOI： 10.1128/AAC.00371-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella.

Authors:  William Wiley Navarre; Steffen Porwollik; Yipeng Wang; Michael McClelland; Henry Rosen; Stephen J Libby; Ferric C Fang
Journal:  Science       Date:  2006-06-08       Impact factor: 47.728

Review 2.  H-NS, the genome sentinel.

Authors:  Charles J Dorman
Journal:  Nat Rev Microbiol       Date:  2006-12-27       Impact factor: 60.633

Review 3.  Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella.

Authors:  Kunihiko Nishino; Eiji Nikaido; Akihito Yamaguchi
Journal:  Biochim Biophys Acta       Date:  2009-02-20

4.  One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.

Authors:  K A Datsenko; B L Wanner
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

5.  Analysis of a complete library of putative drug transporter genes in Escherichia coli.

Authors:  K Nishino; A Yamaguchi
Journal:  J Bacteriol       Date:  2001-10       Impact factor: 3.490

6.  Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops.

Authors:  Christopher A Elkins; Hiroshi Nikaido
Journal:  J Bacteriol       Date:  2002-12       Impact factor: 3.490

7.  Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.

Authors:  M McClelland; K E Sanderson; J Spieth; S W Clifton; P Latreille; L Courtney; S Porwollik; J Ali; M Dante; F Du; S Hou; D Layman; S Leonard; C Nguyen; K Scott; A Holmes; N Grewal; E Mulvaney; E Ryan; H Sun; L Florea; W Miller; T Stoneking; M Nhan; R Waterston; R K Wilson
Journal:  Nature       Date:  2001-10-25       Impact factor: 49.962

8.  RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.

Authors:  Andrew M Bailey; Ian T Paulsen; Laura J V Piddock
Journal:  Antimicrob Agents Chemother       Date:  2008-08-11       Impact factor: 5.191

9.  The AcrB multidrug transporter plays a major role in high-level fluoroquinolone resistance in Salmonella enterica serovar typhimurium phage type DT204.

Authors:  Sylvie Baucheron; Hein Imberechts; Elisabeth Chaslus-Dancla; Axel Cloeckaert
Journal:  Microb Drug Resist       Date:  2002       Impact factor: 3.431

10.  AcrAB multidrug efflux pump regulation in Salmonella enterica serovar Typhimurium by RamA in response to environmental signals.

Authors:  Eiji Nikaido; Akihito Yamaguchi; Kunihiko Nishino
Journal:  J Biol Chem       Date:  2008-06-24       Impact factor: 5.157
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  6 in total

Review 1.  The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Authors:  Xian-Zhi Li; Patrick Plésiat; Hiroshi Nikaido
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

2.  H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing.

Authors:  Umar F Shahul Hameed; Chenyi Liao; Anand K Radhakrishnan; Franceline Huser; Safia S Aljedani; Xiaochuan Zhao; Afaque A Momin; Fernando A Melo; Xianrong Guo; Claire Brooks; Yu Li; Xuefeng Cui; Xin Gao; John E Ladbury; Łukasz Jaremko; Mariusz Jaremko; Jianing Li; Stefan T Arold
Journal:  Nucleic Acids Res       Date:  2019-03-18       Impact factor: 16.971

3.  Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS.

Authors:  Deanna Deveson Lucas; Bethany Crane; Amy Wright; Mei-Ling Han; Jennifer Moffatt; Dieter Bulach; Simon L Gladman; David Powell; Jesus Aranda; Torsten Seemann; Diana Machado; Teresa Pacheco; Teresa Marques; Miguel Viveiros; Roger Nation; Jian Li; Marina Harper; John D Boyce
Journal:  Antimicrob Agents Chemother       Date:  2018-06-26       Impact factor: 5.191

Review 4.  Environmental and genetic modulation of the phenotypic expression of antibiotic resistance.

Authors:  Diarmaid Hughes; Dan I Andersson
Journal:  FEMS Microbiol Rev       Date:  2017-05-01       Impact factor: 16.408

Review 5.  Function and Inhibitory Mechanisms of Multidrug Efflux Pumps.

Authors:  Kunihiko Nishino; Seiji Yamasaki; Ryosuke Nakashima; Martijn Zwama; Mitsuko Hayashi-Nishino
Journal:  Front Microbiol       Date:  2021-12-03       Impact factor: 5.640

6.  A role for the periplasmic adaptor protein AcrA in vetting substrate access to the RND efflux transporter AcrB.

Authors:  Ilyas Alav; Vassiliy N Bavro; Jessica M A Blair
Journal:  Sci Rep       Date:  2022-03-19       Impact factor: 4.379
  6 in total

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